The multifaceted roles of extracellular vesicles for therapeutic intervention with non-Hodgkin lymphoma.

Extracell Vesicles Circ Nucl Acids

The University of Kansas Cancer Center, University of Kansas Medical Center, Kansas City, KS 66160, USA.

Published: June 2024

Extracellular vesicles (EVs) contribute to the development of cancer in various ways. Non-Hodgkin lymphoma (NHL) is a cancer of mature lymphocytes and the most common hematological malignancy globally. The most common form of NHL, diffuse large B-cell lymphoma (DLBCL), is primarily treated with chemotherapy, autologous stem cell transplantation (ASCT), and/or chimeric antigen receptor T-cell (CAR-T) therapy. With NHL disease progression and its treatment, extracellular vesicles play remarkable roles in influencing outcomes. This finding can be utilized for therapeutic intervention to improve patient outcomes for NHL. This review focuses on the multifaceted roles of EVs with NHL and its potential for guiding patient care.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11618822PMC
http://dx.doi.org/10.20517/evcna.2024.07DOI Listing

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