AI Article Synopsis
- The study investigates the effectiveness of probiotics during and after colorectal surgery, focusing on immune function and infection rates.
- It involved 15 patients, with probiotics administered to two groups and a control group, with blood and fecal samples taken for analysis.
- Findings suggest probiotics are safe and may help reduce infections and intestinal inflammation, indicating a need for more research to confirm these benefits.
Article Abstract
Background: The clinical value of probiotics in patients undergoing abdominal surgery, particularly colorectal surgery, remains uncertain despite their well-documented health benefits. This pilot randomized controlled trial aimed to assess the effects of perioperative and postoperative oral administration of two probiotics, Clostridium butyricum CBM588 and Bifidobacterium longum ES1, on immune function, systemic inflammatory response, postoperative infections, and recovery after colorectal surgery.
Methods: Fifteen adult patients underwent colorectal resection, with two groups receiving probiotics and one acting as a control. Blood and fecal samples were collected, and clinical parameters were assessed.
Results: Results showed the safety of probiotics, resistance to antibiotics and gastric acid, and potential benefits in reducing postoperative infections and intestinal inflammation.
Conclusions: Future trials should provide more conclusive evidence on the efficacy and safety of perioperative probiotic administration in colorectal surgery, aiming for improved patient outcomes and reduced healthcare costs.
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| http://dx.doi.org/10.23736/S2724-5985.24.03701-X | DOI Listing |
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