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http://dx.doi.org/10.1017/cjn.2024.350 | DOI Listing |
J Comp Physiol B
January 2025
Department of Ocean Sciences, Memorial University of Newfoundland and Labrador, St. John's, NL, A1C 5S7, Canada.
We developed and validated a surgical technique to measure central venous pressure (CVP) in Nile tilapia, and investigated the effects of an acute temperature decrease (from 30 vs. 24 °C) and changes in heart rate (f) using zatebradine hydrocholoride, which decreases intrinsic f on this species' cardiac function. As predicted, f and cardiac output ( ) were ~ 40% lower in the acutely cooled fish, and both groups had very comparable (i.
View Article and Find Full Text PDFJ Am Coll Cardiol
December 2024
Department of Cardiothoracic Surgery, Weill Cornell Medicine, New York, New York, USA.
CJEM
January 2025
Canadian Association of Emergency Physicians Critical Care Committee, Ottawa, ON, Canada.
Neurooncol Adv
December 2024
Odette Cancer Centre, Department of Medicine, University of Toronto, Toronto, Canada.
Background: The majority of patients diagnosed with glioblastoma are >60 years. Three randomized trials addressed the roles of radiotherapy (RT) and temozolomide (TMZ) for elderly patients. NORDIC and NOA-08 compared RT versus TMZ, while CE.
View Article and Find Full Text PDFJ Neuroinflammation
January 2025
Department of Cerebrovascular Diseases, The Second Affiliated Hospital of Zhengzhou University, 2 Jingba Road, Zhengzhou, Henan, China.
Background: Intracerebral hemorrhage (ICH) causes prominent deposition of extracellular matrix molecules, particularly the chondroitin sulphate proteoglycan (CSPG) member neurocan. In tissue culture, neurocan impedes the properties of oligodendrocytes. Whether therapeutic reduction of neurocan promotes oligodendrogenesis and functional recovery in ICH is unknown.
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