Franz Joseph Haydn was a prominent musician in the late 1700s. Researchers have speculated that Haydn may have suffered from subcortical cerebrovascular disease. These interpretations, based on biographical and other sources, might be accurate. However, given that he lived to the advanced age of 77 years, it is likely he experienced multiple pathological changes in his brain, as is commonly believed. It seems unlikely that a great man would rest in peace, because even 200 years after his death, significant interest in his chronic illnesses is still present.
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Franz Joseph Haydn was a prominent musician in the late 1700s. Researchers have speculated that Haydn may have suffered from subcortical cerebrovascular disease. These interpretations, based on biographical and other sources, might be accurate.
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Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) Helmholtz Center for Infection Research (HZI), Department DDEL, Saarland University, Campus A41, D-66123, Saarbrücken, Germany.
Purpose: Contrary to physical characterization techniques for nanopharmaceuticals (shape, size and zeta-potential), the techniques to quantify the free and the entrapped drug remain very few and difficult to transpose in routine analytical laboratories. The application of Solid Phase Extraction (SPE) technique was investigated to overcome this challenge.
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Joseph Haydn's encephalopathy: new aspects.
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Department of Neurology, Universitätsmedizin Mannheim, University of Heidelberg, Mannheim, Germany.
With increasing age, Joseph Haydn complained of progressive forgetfulness preventing him from composing for about the last 8 years of his life. He spent his days more and more inactive and immobilized, suffering from a disabling gait disturbance. Still, most biographers consider diffuse atherosclerosis and congestive heart failure to be reasons for Haydn's medical condition and physical decline during the last years of his life.
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