AI Article Synopsis
- Biosensors are crucial in life sciences applications, especially in healthcare, for areas like drug development, disease diagnosis, food safety, and environmental monitoring.
- Terahertz (THz) spectroscopy offers a promising label-free and non-invasive method for detecting biomolecules with high sensitivity and speed, making it ideal for biomedical uses.
- The review discusses techniques to enhance biosensor performance, compares existing biosensor technologies, and outlines challenges and future directions for THz-based biosensing.
Article Abstract
Biosensors have many life sciences-related applications, particularly in the healthcare sector. They are employed in a wide range of fields, including drug development, food quality management, early diagnosis of diseases, and environmental monitoring. Terahertz-based biosensing has shown great promise as a label-free, non-invasive, and non-contact method of detecting biological substances. THz Spectroscopy has achieved a remarkable advancement in biomolecule recognition providing a rapid, highly sensitive, and non-destructive approach for various biomedical applications. The significance of THz-based biosensors and the broad spectrum of biomolecules that can be detected and analyzed with biosensors are reviewed in this work. Additionally, this work summarizes several techniques that were previously reported to improve the sensitivity and selectivity of these biosensors. Furthermore, an in-depth comparison between previously developed biosensors with an emphasis on their performance is presented and highlighted in the current review. Lastly, the challenges, the potential, and the future prospects of THz-based biosensing technology are critically addressed.
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| http://dx.doi.org/10.1016/j.ymeth.2024.12.001 | DOI Listing |
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