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Concurrence of idiopathic granulomatous mastitis and breast cancer in a patient on neoadjuvant chemotherapy: A case report. | LitMetric

Concurrence of idiopathic granulomatous mastitis and breast cancer in a patient on neoadjuvant chemotherapy: A case report.

Int J Surg Case Rep

Associate Professor, Department of Breast Surgery, Aga Khan University Hospital, Karachi, Pakistan. Electronic address:

Published: November 2024

AI Article Synopsis

  • Idiopathic Granulomatous Mastitis (IGM) is a rare benign inflammatory condition affecting the breast, often challenging to diagnose.
  • A case study highlights a 45-year-old woman who developed IGM after neoadjuvant chemotherapy for stage II invasive ductal carcinoma, eventually requiring modified radical mastectomy and steroid treatment.
  • There is limited literature on IGM, and existing treatment guidelines are not well-established, complicating management approaches.

Article Abstract

Introduction: Idiopathic Granulomatous Mastitis is a rare benign inflammatory disease of the breast.

Presentation Of The Case: We present a case of 45-year-old woman who was diagnosed with stage II invasive ductal carcinoma in the left breast. While receiving neoadjuvant chemotherapy, she developed idiopathic granulomatous mastitis (IGM) in the left breast after the second cycle. She underwent modified radical mastectomy and has been managed with steroids for IGM on the contralateral side, which developed later in the course of the disease. This is a unique finding with limited literature available on similar cases, to the best of our knowledge.

Discussion: IGM poses a diagnostic challenge requiring histopathology for definitive diagnosis.

Conclusion: Treatment guidelines of IGM are not established making it difficult to manage.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijscr.2024.110702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663975PMC

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