Objective: To assess the applicability of the parent attitudes about childhood vaccines (PACV) survey to pet owners and its association with vaccine hesitancy.
Methods: A national survey including an adapted version of the PACV was administered to 2,853 dog and 1,977 cat owners. Respondents were queried about the vaccination status of their pets. Exploratory factor analysis, Mokken scale analysis, Cronbach α, McDonald ω, and bivariate analyses were used to assess the validity and reliability of the PACV and shortened versions. The Fisher exact test and linear probability models were used to assess the association between the PACV and other factors and vaccination status.
Results: The PACVs for pet owners were valid and reliable with high internal consistency and served as correlates for vaccination status. In multivariate analyses, long-term relationships with veterinarians were also associated with vaccination. Individual survey items indicated substantial concerns about vaccine safety, side effects, and efficacy. Most respondents indicated trust and good relationships with their veterinarian, had not avoided or delayed vaccinations, understood the severity of pet diseases, supported the recommended vaccine schedule, and did not self-identify as vaccine hesitant (VH). The PACV identified 21.7% of dogs and 25.9% of cat owners as VH.
Conclusions: The full and the reduced versions of the PACV are valid and reliable tools to assess VH status in dog and cat owners.
Clinical Relevance: The PACV could serve as an important tool for veterinary researchers to identify factors associated with vaccine hesitancy and develop effective interventions.
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http://dx.doi.org/10.2460/ajvr.24.06.0163 | DOI Listing |
PLoS Med
January 2025
University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Background: Nirmatrelvir with ritonavir (Paxlovid) is indicated for patients with Coronavirus Disease 2019 (COVID-19) who are at risk for progression to severe disease due to the presence of one or more risk factors. Millions of treatment courses have been prescribed in the United States alone. Paxlovid was highly effective at preventing hospitalization and death in clinical trials.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Statistics, Shahjalal University of Science & Technology, Sylhet, Bangladesh.
Background: Maternal tetanus toxoid (MTT) vaccination during pregnancy remains an important factor for reducing infant mortality globally, especially in developing nations, including Bangladesh. Despite commendable progress in reducing child mortality through widespread MTT vaccination during pregnancy, the issue still exists. This analysis explores the impact of MTT vaccination on neonatal mortality in Bangladesh and identifies associated factors.
View Article and Find Full Text PDFAntimicrob Steward Healthc Epidemiol
July 2024
Department of Pediatrics, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Objective: We aimed to assess risk of COVID-19 infection & seroprotection status in healthcare workers (HCWs) in both hospital and community settings following an intensive vaccination drive in India.
Setting: Tertiary Care Hospital.
Methods: We surveyed COVID-19 exposure risk, personal protective equipment (PPE) compliance, vaccination status, mental health & COVID-19 infection rate across different HCW cadres.
EClinicalMedicine
August 2024
Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Background: In an interim analysis of this phase 2 trial, adding the GX-188E vaccine to pembrolizumab resulted in manageable toxicity with antitumor activities in patients with recurrent or advanced cervical cancer. Here, we report the final safety and efficacy results after a long-term follow-up at the study's completion.
Methods: This open-label, single-arm, phase II trial was conducted in nine hospitals in South Korea (ClinicalTrials.
Cureus
December 2024
Internal Medicine, Sultan Bin Abdulaziz Humanitarian City, Riyadh, SAU.
Background The safety and adverse effects (AEs) associated with approved COVID-19 vaccines in individuals with multiple sclerosis (MS) require further examination, particularly as there is limited information available for MS patients in Saudi Arabia. This study sought to investigate the reported AEs of COVID-19 vaccines among MS patients admitted to a major rehabilitation center in Saudi Arabia. Methods A cross-sectional analysis was conducted from January 2023 to March 2024 at Sultan Bin Abdulaziz Humanitarian City (SBAHC) in Riyadh.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!