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http://dx.doi.org/10.15585/mmwr.mm7348a4 | DOI Listing |
Curr Cancer Drug Targets
January 2025
Department of Chemistry, Siddhachalam Laboratory, Raipur, 493221, Chhattisgarh, India.
Objectives: The primary objective of this review is to provide updated mechanisms that regulate ferroptosis sensitivity in cancer cells and recent advancements in drug targeting for ferroptosis as an antitumor therapy.
Methods: To achieve these objectives, a comprehensive literature review was conducted, analyzing recent studies on ferroptosis, including its cellular, molecular, and gene-level characteristics. The review involved an evaluation of advancements in ferroptosis drug research across various medical domains, with particular attention to novel therapeutic approaches in nano-medicine, TCM, and Western medicine.
BMC Nutr
January 2025
Department of Public Health , Institute of Health Sciences, Wollega University, Nekemte Town, Post Box 395, Nekemte, Oromia, Ethiopia.
Background: Adult patients suffering from malnutrition in hospitals are often overlooked, especially in low-income countries. Health care professionals play a vital role in identifying and managing the nutritional needs of patients. However, their perception regarding the nutritional care of adult patients have not been thoroughly examined.
View Article and Find Full Text PDFBMC Res Notes
January 2025
Department of Epidemiology and Disease Control, School of Public Health, University of Ghana, Accra, Ghana.
Background: This study evaluated Health Care Workers' (HCWs) knowledge, attitude, perceived compliance, and potential influencing factors related to Infection Prevention and Control (IPC) standards in the North Bank East region of The Gambia.
Method: The study was an analytic cross-sectional study, conducted in 2021 using a multistage sampling technique. Thirteen health facilities were sampled from the North Bank East Region of The Gambia.
JMIR Med Educ
January 2025
Department of Medical Education, Center for Innovative Medical Education, Jagiellonian University Medical College, Kraków, Poland.
Background: Concept maps are a suitable method for teaching clinical reasoning (CR). For example, in a concept map, findings, tests, differential diagnoses, and treatment options can be documented and connected to each other. When combined with virtual patients, automated feedback can be provided to the students' concept maps.
View Article and Find Full Text PDFFront Genet
January 2025
Pediatric Translational Medicine Institute and Pediatric Congenital Heart Disease Institute, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Macrophages are known to support cardiac development and homeostasis, contributing to tissue remodeling and repair in the adult heart. However, it remains unclear whether embryonic macrophages also respond to abnormalities in the developing heart. Previously, we reported that the structural protein Sorbs2 promotes the development of the second heart field, with its deficiency resulting in atrial septal defects (ASD).
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