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Experiences and perceptions of respectful maternity care among mothers during childbirth in health facilities of Eastern province of Rwanda: An appreciative inquiry.
PLoS One
January 2025
School of Nursing and Midwifery, University of Rwanda, Kigali, Rwanda.
Introduction: The World Health Organization (WHO) has emphasized the importance of ensuring respectful and dignified childbirth experiences. However, many countries, including Rwanda, have documented negative experiences during childbirth. Identifying best practices can help uncover sustainable solutions for resource-limited settings rather than focusing solely on the challenges and negative aspects.
View Article and Find Full Text PDFNeoadjuvant atezolizumab in combination with dual HER2 blockade plus epirubicin in women with early HER2-positive breast cancer: the randomized phase 2 ABCSG-52/ATHENE trial.
Nat Cancer
January 2025
Department of Internal Medicine III with Hematology, Medical Oncology, Hemostaseology, Infectiology and Rheumatology, Oncologic Center, Paracelsus Medical University Salzburg, Salzburg Cancer Research Institute, Center for Clinical Cancer and Immunology Trials (SCRI-CCCIT), Cancer Cluster Salzburg, Salzburg, Austria.
The role of anthracyclines in the treatment of early breast cancer (EBC) is increasingly being challenged, especially in de-escalation strategies. However, owing to their immunogenic effects, anthracyclines are promising combination partners with immunotherapies. In the randomized phase 2 trial ABCSG-52 (EudraCT no.
View Article and Find Full Text PDFTo Seclude or Not to Seclude? Using Grounded Theory to Develop a Model of the Seclusion Decision-Making Process Used by Mental Health Nurses in Forensic Services.
Issues Ment Health Nurs
January 2025
Department of Applied Psychology, Cardiff Metropolitan University, Cardiff, United Kingdom.
Seclusion is a restrictive intervention used in forensic mental health care to manage service user risk of harm. It has been associated with harmful effects for service users and consensus is that its use needs to be reduced. Research has identified that factors related to nursing staff influence the use of seclusion.
View Article and Find Full Text PDFBackground: LIGHT (oLaparib In HRD-Grouped Tumor types; NCT02983799) prospectively evaluated olaparib treatment in patients with platinum-sensitive relapsed ovarian cancer (PSROC) assigned to cohorts by known BRCA mutation (BRCAm) and homologous recombination deficiency (HRD) status: germline BRCAm (gBRCAm), somatic BRCAm (sBRCAm), HRD-positive non-BRCAm, and HRD-negative. At the primary analysis, olaparib treatment demonstrated activity across all cohorts, with greatest efficacy in terms of objective response rate and progression-free survival observed in the g/sBRCAm cohorts. The authors report final overall survival (OS).
View Article and Find Full Text PDFImportance of transgender nuances in research and advocacy: Reply to Morgenroth (2025) and Tate (2025).
Br J Psychol
January 2025
School of Psychological Sciences, Macquarie University, Sydney, New South Wales, Australia.
In their responses to our paper 'Conceptualizing transgender experiences in psychology: Do we have a "true" gender?' (The British Journal of Psychology, 2024, 115, 723), Tate (2025) and Morgenroth (2025) provide reflections on the importance of nuance when researching gender and in transgender advocacy. In this reply, I note where this paper is situated in the literature and engage in a discussion of the role of definitions in transgender advocacy. Over-reliance on an individual's true gender when evaluating transgender people's legitimacy may exclude individuals whose gender is not understandable as 'true' to a cisgender majority.
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