Calcium and vitamin D substitution for hypoparathyroidism after thyroidectomy - how is it continued after discharge from hospital?

Langenbecks Arch Surg

Section of Endocrine Surgery, Department of General, Visceral and Transplantation Surgery, University Medical Center, Johannes Gutenberg University Mainz, Langenbeckstraße 1, D-55131, Mainz, Germany.

Published: December 2024

AI Article Synopsis

  • The study focuses on managing postoperative hypoparathyroidism (HypoPT) after thyroid surgery, which often requires calcium and active vitamin D supplements.
  • During a retrospective analysis from March 2015 to December 2023 at UMC Mainz, it was found that only 28.3% of patients continued receiving these supplements post-discharge, despite varying levels of parathyroid hormone (PTH) and calcium.
  • The results highlighted inconsistencies in how external practitioners adjust these supplements, suggesting that thyroid surgeons should recommend a structured reduction plan to prevent excessive calcium intake and potential kidney issues.

Article Abstract

Purpose: Postoperative hypoparathyroidism (HypoPT) is one of the most feared complications after thyroid surgery. In most cases, HypoPT is transient, requiring temporary substitution with calcium and active vitamin D. The analysis was conducted to investigate how calcium and vitamin D substitution was managed in routine postoperative clinical practice after discharge from hospital.

Methods: From March 2015 to December 2023, patients with HypoPT after thyroidectomy at the university medical center (UMC) Mainz, were included in a retrospective study. The rate of continued prescription of calcium and vitamin D by external practitioners in relation to the PTH and calcium levels at the first postoperative outpatient visit at the outpatient clinic of the UMC Mainz was analyzed and critically discussed.

Results: Ninety-four of 332 patients (28.3%) were continuously prescribed with calcium/vitamin D supplements: 14 had PTH deficiency and hypocalcemia and 14 had normal/elevated PTH levels with hypocalcemia, 59 had PTH values below the normal range and normo- or hypercalcemia and 7 had normal or elevated PTH levels with normocalcemia.

Conclusions: There are inconsistent procedures regarding the adjustment of the calcium and vitamin D substitution by the practices providing external follow-up treatment. To avoid iatrogenic suppression of PTH levels, high calcium load and potential affection of the kidney function, a reduction scheme should be actively recommended by thyroid surgeons.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11621183PMC
http://dx.doi.org/10.1007/s00423-024-03556-wDOI Listing

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