Despite recent developments in positron emission tomography technology, cardiac single photon emission computed tomography (SPECT) imaging continues to be the main stream of nuclear cardiology because of its high accessibility and wider clinical use. For SPECT imaging, cadmium-zinc telluride (CZT) based detectors have advantages over conventional Anger type detectors with more flexible camera design thanks to the small sized CZT detectors and high contrast imaging because of its high energy resolution. Approximately 15 years ago, CZT-based cardiac SPECT cameras became commercially available, resulting in great success in clinical practice. However, this was just the beginning of the CZT era. To date, CZT-based general purpose whole-body camera and 3 dimensional full-ring SPECT systems have been developed and become commercially available with promising initial results. Although there still are areas to be addressed before wider clinical use, the CZT-based technology may provide significant progresses in nuclear cardiology as new generation SPECT systems. Finally, newer materials for the semiconductor detectors are under investigation or development, suggesting that there will be more developments in cardiac SPECT technology.
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http://dx.doi.org/10.17996/anc.24-00011 | DOI Listing |
Phys Eng Sci Med
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Radiation Application Research School, Nuclear Science and Technology Research Institute (NSTRI), Tehran, 14155-1339, Iran.
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Pharma Research and Early Development (pRED), Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
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View Article and Find Full Text PDFAsia Ocean J Nucl Med Biol
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Department of Nuclear Medicine, Saitama Medical University Hospital, Saitama, Japan.
Clin Radiol
December 2024
Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210029, China. Electronic address:
Aim: Coronary artery disease (CAD) is a primary cause of mortality, prompting ongoing research into noninvasive diagnostic modalities. This study aimed to evaluate the diagnostic efficacy of exercise electrocardiography testing (EET) combined with cadmium zinc tellurium cardiac-dedicated single photon emission computed tomography (CZT-SPECT) imaging for CAD.
Materials And Methods: CZT-SPECT and EET were examined in 124 patients aged 20-85 years, followed by coronary angiography to evaluate the sensitivity, specificity, positive predictive value, and negative predictive value of EET/CZT-SPECT alone and in combination.
Study Objectives: To evaluate the capability and accuracy of magnetocardiography (MCG) to identify patients with ischemic chest pain from those with non-ischemic pain and to verify normalcy in the MCG in healthy subjects.
Design: We studied 133 patients (mean age 59 ± 14 years, 69 % male) with chronic or acute chest pain syndrome and 63 healthy subjects (mean age 41.7 ± 12.
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