Increased incidence of uterine leiomyoma in young females with depression: An observational study.

iScience

Department of Obstetrics and Gynecology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.

Published: October 2024

AI Article Synopsis

  • A study of over 2.5 million young females showed that those with depression had a higher likelihood of developing uterine leiomyoma compared to those without depression.
  • The risk of developing these tumors was notably greater in individuals with recurrent depression.
  • It is recommended that young females with depression undergo screening for uterine leiomyoma, especially if they are older or have cholesterol issues.

Article Abstract

Based on analyses of 22,487,947 person-years of follow-up data in a cohort of 2,523,565 young females, we found that the presence of depression was associated with a higher cumulative incidence of new-onset uterine leiomyoma than the absence of depression. This risk was even higher in patients with recurrent depression, and depression had a significant interaction with relatively old age and dyslipidemia. Screening for uterine leiomyoma is advisable in young females experiencing depression, as they appear to be at increased risk for developing this tumor type.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11615256PMC
http://dx.doi.org/10.1016/j.isci.2024.110896DOI Listing

Publication Analysis

Top Keywords

uterine leiomyoma
12
young females
12
depression
6
increased incidence
4
incidence uterine
4
leiomyoma young
4
females depression
4
depression observational
4
observational study
4
study based
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!