Purpose: To evaluate the impact of delaying reconstruction following anterior cruciate ligament (ACL) injury on the risk of meniscal injury and subsequent meniscectomy, the study was carried out. This constitutes the first study of its kind to be conducted in China.
Methods: This study collected data on patients who had undergone ACL reconstruction surgery at Peking University First Hospital between 2010 and 2022. Patient's injury details, including the time and cause of ACL injury, surgery date and meniscal injury details, were recorded. Patients were stratified into distinct cohorts based on the duration between injury and reconstruction. Logistic regression analysis was used to evaluate the impact of a delayed reconstruction time on the risk of meniscal injury and meniscectomy.
Results: The study involved patients with an average age of 34.1 ± 11.3 years. Nearly half of the patients (49.74%) had meniscal injuries. Univariate logistic regression analysis showed that gender and the time from ACL trauma to surgery were significantly associated with meniscus injury ( < 0.01). Men have a higher risk of meniscus damage than women ( < 0.01, odds ratio: 1.94, 95% confidence interval: 1.23-3.05). Patients who had surgery 12 months after injury had a significantly increased risk of meniscus injury compared to those who had surgery within 3 months after injury ( < 0.01). The time from ACL injury to operation was significantly correlated with medial meniscus injury ( < 0.001). There was no significant correlation between time to ACL reconstruction and lateral meniscus injury ( > 0.05). Age was significantly associated with the risk of medial meniscectomy ( > 0.05). Time from injury to surgery was not significantly associated with the risk of lateral meniscectomy ( > 0.05).
Conclusions: Delayed reconstruction beyond 12 months after ACL rupture increases the risk of medial meniscus injury. The risk of meniscus injury after ACL injury is higher in men than in women, and the risk of medial meniscectomy increases with age.
Level Of Evidence: Level III.
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http://dx.doi.org/10.1002/jeo2.70101 | DOI Listing |
Am J Sports Med
January 2025
North Sydney Orthopaedic and Sports Medicine Centre, Wollstonecraft, New South Wales, Australia.
Background: A growing body of evidence surrounds secondary meniscal and cartilage pathology after delay to anterior cruciate ligament (ACL) reconstruction (ACLR). Many of these studies focus on or include an adult population.
Purpose: To elucidate the prevalence of secondary meniscal and chondral pathology with delay to ACLR in the adolescent population as well as examine the influence of sex, skeletal maturity, and trends over the years.
J Clin Med
December 2024
Department of Orthopedics, Akron Children's Hospital, Akron, OH 44307, USA.
The management of anterior cruciate ligament (ACL) injuries in pediatric patients presents unique challenges due to the presence of open growth plates in the proximal tibia and distal femur. Delaying ACL reconstruction until skeletal maturity may protect the physes but increases the risk of secondary injuries, such as meniscal tears and chondral damage, due to prolonged joint instability. Conversely, early surgical intervention restores knee stability but raises concerns about potential growth disturbances, including leg-length discrepancies and angular deformities.
View Article and Find Full Text PDFAm J Sports Med
January 2025
Department of Orthopaedics, Warren Alpert Medical School of Brown University/Rhode Island Hospital, Providence, Rhode Island, USA.
Background: Meniscal injuries that fail to heal instigate catabolic changes in the knee's microenvironment, posing a high risk for developing posttraumatic osteoarthritis (PTOA). Previous research has suggested that human cartilage-derived progenitor cells (hCPCs) can stimulate meniscal repair in a manner that depends on stromal cell-derived factor 1 (SDF-1) pathway activity.
Hypothesis: Overexpressing the SDF-1 receptor CXCR4 in hCPCs will increase cell trafficking and further improve the repair efficacy of meniscal injuries.
Cureus
December 2024
Pharmacy, Kafr El Sheikh General Hospital, Kafr El Sheikh, EGY.
Medial meniscus root tears (MMRTs) are serious injuries that disrupt knee biomechanics, often accelerating cartilage degeneration and osteoarthritis when left untreated. These injuries are increasingly recognized as a major cause of knee pain and functional limitations, particularly among middle-aged and older adults. This systematic review and meta-analysis aimed to evaluate the outcomes of conservative management compared to surgical intervention for MMRT, focusing on pain relief, functional recovery, and the progression of osteoarthritis.
View Article and Find Full Text PDFBMC Musculoskelet Disord
January 2025
Department of Orthopaedics and Traumatology, Faculty of Medicine, Dokuz Eylül University, İzmir, 35340, Turkey.
Background: Menisci, one of the most important anatomical structures of the knee joint, plays a role in load transfer, stability, shock absorption, prevention of articular cartilage degeneration, and proprioception. Type I collagen, the main component of the meniscus, and type II collagen fibers play an important role in the stability of the knee joint. This study aimed to evaluate the effects of Naturagen® 4 Joint product containing type I, II, and III collagen on pain, quality of life, and physical functions in patients with meniscopathy.
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