AI Article Synopsis
- The study investigated the use of ABC/2 for measuring infarct volume in stroke patients with ASPECTS less than 6 undergoing mechanical thrombectomy (MT).
- Patients treated with MT demonstrated better recovery outcomes compared to those receiving standard drug therapy, including higher rates of favorable modified Rankin Scale scores and lower mortality rates, despite an increased risk of intracranial hemorrhage.
- The research concludes that ABC/2 is a practical measurement tool for infarct volume in these patients when advanced imaging isn't available.
Article Abstract
Objective: We aimed to determine whether the ABC/2 can be used as an infarct volume measurement tool for Mechanical thrombectomy (MT) in patients with Alberta Stroke Program Early CT Scores (ASPECTS) < 6.
Methods: Patients with stroke with ASPECTS <6 within 24 h were included in this study, and infarct volume was measured using the ABC/2. The patients were categorized into MT and standard drug groups. They were assessed based on a modified Rankin Scale (mRS) ≤3 at 3 months, intracranial hemorrhage within 48 h, and mortality at 3 months.
Results: ASPECTS <6 showed a significant negative correlation with infarct volume measured using the ABC/2. Compared to drug therapy, the patients who received MT treatment had a higher proportion of achieving an mRS score of ≤3 (OR, 2.60; 95 % confidence interval [CI], 1.04-6.50; P = 0.040), a lower death rate (OR, 0.37; 95 % CI, 0.15-0.92; P = 0.031), and a reduced decompressive craniectomy (OR, 0.10; 95 % CI, 0.01-0.83; P = 0.033); however, intracranial hemorrhage risk significantly increased (OR, 4.35; 95 % CI, 1.12-17.0; P = 0.034).
Conclusion: In the absence of advanced imaging, the ABC/2 can be a useful tool for measuring volume in anterior circulation in patients with ASPECTS <6.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11616561 | PMC |
| http://dx.doi.org/10.1016/j.heliyon.2024.e40421 | DOI Listing |
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