Gender differences in the incidence of saphenous vein graft intervention.

J Cardiothorac Surg

Department of Cardiology, Barzilai Medical Center, The Ben-Gurion University of the Negev, Hahistadrout 2, 7830604, Ashkelon, Israel.

Published: December 2024

AI Article Synopsis

  • The study investigated gender differences in outcomes of saphenous vein graft percutaneous coronary intervention (SVG PCI) after coronary artery bypass grafting (CABG) among patients treated for acute coronary syndrome (ACS).
  • Researchers analyzed data from 72 patients at Barzilai Medical Center between 2010 and 2023, finding that men had higher SVG PCI rates, while women experienced earlier graft failures.
  • The findings suggest that gender-specific strategies in post-CABG care could enhance patient outcomes and emphasize the importance of tailoring follow-up interventions based on patient gender.

Article Abstract

Background: Saphenous vein graft percutaneous coronary intervention (SVG PCI) following coronary artery bypass grafting (CABG) is commonly used procedure for patients presenting with acute coronary syndrome (ACS). Emerging evidence suggests gender-based differences influencing SVG intervention clinical outcomes. This study aimed to analyze the impact of gender and various patient characteristics, procedural intricacies, anatomical considerations, and perioperative factors as potential risk determinants for SVG failure post-CABG surgery.

Methods: A retrospective, single-center, analysis was conducted on post-CABG patients at Barzilai Medical Center Ashkelon from 2010 to 2023 to assess gender-based differences in SVG PCI incidence.

Results: Of the 72 ACS patients undergoing SVG PCI, a notably higher incidence was observed in men. However, graft failure occurred earlier in women compared to men (13.50 ± 6.59 SD years vs. 22.13 ± 5.66 SD years). Women exhibited a 1.2 times higher likelihood of earlier PCI than men (OR 1.24 CI 1.077 to 1.487, p = 0.0066) after adjusting for age, smoking, diabetes, hypertension, and hyperlipidemia.

Conclusion: Gender differences in the incidence of SVG PCI and graft failure denote the need for gender-tailored follow-up and early intervention to optimize graft patency and potentially enhance long-term clinical outcomes. Integrating gender-specific approaches into post-CABG management could significantly improve patient care and prognosis.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11619639PMC
http://dx.doi.org/10.1186/s13019-024-03139-2DOI Listing

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