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Rectal mast cell tumour in a dog with lower grade features of biological aggressiveness. | LitMetric

Rectal mast cell tumour in a dog with lower grade features of biological aggressiveness.

Aust Vet J

Advanced Vetcare, Level 1, 26 Robertson Street, Kensington, Victoria, 3031, Australia.

Published: December 2024

AI Article Synopsis

  • An 8-year-old Australian Silky Terrier exhibited symptoms like lethargy, shaking, and lack of appetite, leading to a veterinary visit where a rectal mass was discovered.
  • The mass was surgically removed and identified as a low-grade mast cell tumor (MCT) with a mitotic count of 0, suggesting less aggressive behavior.
  • Following the surgery, the dog underwent a chemotherapy regimen and, 30 weeks later, showed no signs of tumor recurrence and remained healthy at the 9-month mark, indicating a potentially better prognosis than previously reported for similar cases.

Article Abstract

An 8-year-old, neutered female, Australian Silky Terrier presented to her primary veterinarian with non-specific clinical signs of general unwellness, shaking, lethargy, inappetence and no defecation for 2-3 days. A rectal mass was found on physical examination. The rectal mass was surgically resected and histopathology was consistent with a mast cell tumour (MCT) with a mitotic count of 0 per 2.37mm. The dog had follow-up chemotherapy protocol comprising of vinblastine and prednisolone and was doing well with no evidence of tumour recurrence 30 weeks post surgical resection and is still alive and clinically normal at the time of writing, 9 months post initial diagnosis. Primary MCTs of the gastrointestinal tract have previously been reported to be associated with a poor prognosis. This is the first report of a canine rectal mast cell tumour with lower grade features of biological aggressiveness and a possibly more favourable prognosis compared with the current published literature.

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Source
http://dx.doi.org/10.1111/avj.13402DOI Listing

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