While defects are undesirable for the reliability of electronic devices, particularly in scaled microelectronics, they have proven beneficial in numerous quantum and energy-harvesting applications. However, their potential for new computational paradigms, such as neuromorphic and brain-inspired computing, remains largely untapped. In this study, we harness defects in aggressively scaled field-effect transistors based on two-dimensional semiconductors to accelerate a stochastic inference engine that offers remarkable noise resilience. We use atomistic imaging, density functional theory calculations, device modeling, and low-temperature transport experiments to offer comprehensive insight into point defects in WSe FETs and their impact on random telegraph noise. We then use random telegraph noise to construct a stochastic encoder and demonstrate enhanced inference accuracy for noise-inflicted medical-MNIST images compared to a deterministic encoder, utilizing a pre-trained spiking neural network. Our investigation underscores the importance of leveraging intrinsic point defects in 2D materials as opportunities for neuromorphic computing.
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http://dx.doi.org/10.1038/s41467-024-54283-1 | DOI Listing |
Sci Rep
December 2024
ETH Zurich, Zurich, Switzerland.
Artificial intelligence (AI) provides considerable opportunities to assist human work. However, one crucial challenge of human-AI collaboration is that many AI algorithms operate in a black-box manner where the way how the AI makes predictions remains opaque. This makes it difficult for humans to validate a prediction made by AI against their own domain knowledge.
View Article and Find Full Text PDFEur J Obstet Gynecol Reprod Biol
December 2024
Department of Obstetrics and Gynecology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Purpose: To determine the reference values for the shock index (SI) in postpartum patients undergoing elective cesarean delivery with regional anesthesia.
Methods: This prospective study was conducted at our tertiary center between August 1, 2023, and March 1, 2024. We calculated the reference values for the SI within the first 48 h postpartum for patients who underwent elective cesarean delivery after the 34th week of gestation.
PLoS One
December 2024
Department of Obstetrics and Gynaecology, West China Second University Hospital, Sichuan University, Chengdu, China.
Background: Mirvetuximab Soravtansine (MIRV) is a promising antibody‒drug conjugate (ADC) that targets folate receptor alpha (FRα), which is overexpressed in several types of solid tumors. In November 2022, MIRV was approved in the USA for the treatment of adult patients with FRα-positive, platinum-resistant epithelial ovarian, fallopian tube or primary peritoneal cancer who received 1-3 prior systemic treatment regimens. Therefore, high-quality evidence for its efficacy and safety in different cancers is urgently needed.
View Article and Find Full Text PDFDiseases
December 2024
Department of Maxillofacial Surgery, University Hospital of Dubrava, 10000 Zagreb, Croatia.
Oral squamous cell carcinoma (OSCC) causes considerable morbidity and mortality rates, posing a major global health burden. The management of the OSCC is multidisciplinary, but still the gold standard is surgical resection and reconstruction of the postablative defect. The appearance of secondary primary OSCC is not uncommon; however, it is quite rare that it appears on the skin of the flap that was used for reconstruction during the previous surgical therapy.
View Article and Find Full Text PDFObjective: In preterm and very low birth weight (VLBW) infants, attention-related problems have been found to be more pronounced and emerge later as academic difficulties that may persist into school age. In response, based on three attention networks: alerting, orienting, and executive attention, we examined the development of attention functions at 42 months (not corrected for prematurity) as a follow-up study of VLBW ( = 23) and normal birth weight (NBW: = 48) infants.
Method: The alerting and orienting attention networks were examined through an overlap task with or without warning signal.
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