Background: Millions of people live with dementia worldwide, relying heavily on family caregivers. Pain is common in both people living with Alzheimer's disease (PLWAD) and their caregivers, contributing to stress and burden. To our knowledge, this is the first study to examine the relationship between pain, stress, hair cortisol, and mental health in PLWAD and their caregivers and how these factors are linked to caregiver burden.
Methods: This exploratory pilot study included five PLWAD-caregiver dyads. Participants completed questionnaires on pain, mental health, and demographics. Hair samples were collected for cortisol analysis. Pearson correlation coefficients (r) were used to assess relationships between various factors of PLWAD and their caregivers.
Results: Contrary to expectations, pain and mental health measures for PLWAD displayed a trend toward negative correlation with their hair cortisol levels. Conversely, caregiver pain and mental health measures had a trend toward positive correlation with their hair cortisol levels. There was also a trend that higher pain in PLWAD was associated with higher caregiver burden.
Conclusion: This exploratory pilot study showed associational trends suggesting a complex relationship between pain, mental health, and stress in PLWAD-caregiver dyads. This preliminary work will inform future studies that can help advance targeted, tailored interventions.
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http://dx.doi.org/10.1016/j.pmn.2024.10.010 | DOI Listing |
Nurs Inq
January 2025
Medical Surgical Nursing Department, Faculty of Nursing, Alexandria University, Alexandria, Egypt.
Toxic workplace environments, especially those involving gaslighting, are known to contribute to stress and excessive work habits, such as workaholism, which may hinder a nurse's agility-an essential skill in adapting to fast-paced healthcare environments. However, the interplay between workplace gaslighting, workaholism, and agility in nursing remains underexplored. This study aims to investigate the relationship between workplace gaslighting, workaholism, and agility among nurses, focusing on how gaslighting moderates this relationship.
View Article and Find Full Text PDFHealth Info Libr J
January 2025
Sam Jonah Library, University of Cape Coast, Cape Coast, Ghana.
Background: Although university students are young and seem generally healthy, they do have health information needs that affect their academic work. Some university healthcare services and academic libraries collaborated during the COVID-19 pandemic to provide health information to students.
Aims/objectives: The study explored the health information gap among undergraduate students in universities in Ghana.
Environ Res Health
March 2025
Department of Public Health Sciences, School of Medicine, University of California, Davis, United States of America.
Wildfires are impacting communities globally, with California wildfires often breaking records of size and destructiveness. Knowing how communities are affected by these wildfires is vital to understanding recovery. We sought to identify impacted communities' post-wildfire needs and characterize how those needs change over time.
View Article and Find Full Text PDFCurr Epidemiol Rep
June 2024
Department of Epidemiology, Mailman School of Public Health, Columbia University, NY, NY.
Purpose Of Review: Our review critically examines research on trends in mental health among US adults following the COVID-19 pandemic's onset and makes recommendations for research on the topic.
Recent Findings: Studies comparing pre-pandemic nationally representative government surveys ("benchmark surveys") with pandemic-era non-benchmark surveys generally estimated 3-4-fold increases in the prevalence of adverse mental-health outcomes following the pandemic's onset. However, studies analyzing trends in repeated waves of a single survey, which may carry a lower risk of bias, generally estimated much smaller increases in adverse outcomes.
The metabolism of steroids by the gut microbiome affects hormone homeostasis, impacting host development, mental health, and reproductive functions. In this study, we identify the Δ -3-ketosteroid 5β-reductase, 3β-hydroxysteroid dehydrogenase/Δ isomerase, and Δ -3-ketosteroid reductase enzyme families encoded by common human gut bacteria. Through phylogenetic reconstruction and mutagenesis, We show that 5β-reductase and Δ -3-ketosteroid reductase have evolved to specialize in converting diverse 3-keto steroid hormones into their 5β- and Δ -reduced derivatives.
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