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Severe Diffuse Ulcerative Esophagitis Caused by Epstein-Barr Virus/Cytomegalovirus Coinfection in an Immunocompetent Individual.
ACG Case Rep J
January 2025
Department of Gastroenterology, All India Institute of Medical Sciences, Jodhpur, India.
Cytomegalovirus (CMV) and Epstein-Barr virus (EBV) are important causes of viral esophagitis mainly in immunocompromised individuals. Both viruses lead to development of focal ulcerations in the esophagus. While there have been rare case reports of esophagitis in immunocompetent individuals, there has not been a single reported case of coinfection with both CMV and EBV in an immunocompetent individual and presenting with diffuse esophageal ulceration.
View Article and Find Full Text PDFEsophagitis in an immunocompetent patient: A diagnostic challenge.
Eur J Intern Med
December 2024
Department of Infectious Diseases and Laboratory Medicine, Kanazawa University, Kanazawa 920-8641, Ishikawa, Japan.
Chemotherapy combined with immune checkpoint inhibitors may overcome the detrimental effect of high neutrophil-to-lymphocyte ratio prior to treatment in esophageal cancer patients.
Front Oncol
October 2024
Division of Medical Oncology, Department of Medicine, Showa University School of Medicine, Tokyo, Japan.
Introduction: Immune checkpoint inhibitors (ICIs) have emerged as a promising treatment option for esophageal cancer (EC). Although ICIs enable long-term survival in some patients, the efficacy of ICIs varies widely among patients. Therefore, predictive biomarkers are necessary for identifying patients who are most likely to benefit from ICIs to improve the efficacy of the treatment.
View Article and Find Full Text PDFTwo Sides of the Same Coin: Eosinophilic and Herpetic Esophagitis in an Immunocompetent Young Adult.
Rev Esp Enferm Dig
October 2024
Gastroenterology, Unidade Local de Saúde de Santo António.
Dear Editor, We report a case of a 30-year-old woman with an 8-year diagnosis of eosinophilic esophagitis (EoE) treated with swallowed fluticasone propionate throughout this period. She presented to the emergency room with a two-day history of severe odynophagia, aphagia, retrosternal pain, and fever. The patient was febrile and hemodynamically stable, with no visible oropharyngeal lesions.
View Article and Find Full Text PDFHerpes Simplex Virus Esophagitis in an Immunocompetent Patient: A Case Report.
Cureus
September 2024
Department of Medical Gastroenterology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education & Research (DMIHER), Wardha, IND.
Even though it is rare, herpes simplex virus (HSV) esophagitis has a significant adverse impact on immunocompromised people, such as those with HIV, cancer patients receiving chemotherapy or radiation to the neck, and recipients of transplants receiving immunosuppressive treatments. This makes a high level of clinical suspicion necessary for a precise diagnosis and successful treatment. Although rare, its occurrence in immunocompetent patients poses unique challenges for diagnosis and therapy.
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