A PHP Error was encountered

Severity: Warning

Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests

Filename: helpers/my_audit_helper.php

Line Number: 176

Backtrace:

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 176
Function: file_get_contents

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 250
Function: simplexml_load_file_from_url

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 1034
Function: getPubMedXML

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3152
Function: GetPubMedArticleOutput_2016

File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global

File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword

File: /var/www/html/index.php
Line: 316
Function: require_once

[Epidemiological and clinical characteristics of respiratory syncytial virus infections in children in Jiangsu Province, 2014-2023]. | LitMetric

AI Article Synopsis

  • The study examines RSV infections in children aged 0-14 years in Jiangsu Province over a nine-year period, focusing on clinical and epidemiological traits by analyzing data from two hospitals.
  • Of the 4,946 acute respiratory infection cases, RSV was found in 8.21%, with a notable change in positive rates from 10.92% (2014-2019) to 6.06% (2019-2023), indicating significant fluctuations in infection patterns and seasonal intensity.
  • Clinical symptoms were predominantly cough, fever, and shortness of breath, with a higher incidence rate in younger children and in hospital settings compared to outpatient cases, particularly highlighting the increased severity in those under 6 months old.

Article Abstract

To analyze the epidemiological and clinical characteristics of respiratory syncytial virus (RSV) infection in children in Jiangsu Province from 2014 to 2023. The acute respiratory infection cases in children aged 0-14 years were selected from outpatient/emergency or inpatient departments in 2 surveillance sentinel hospitals, respectively, in Nanjing, Suzhou and Taizhou of Jiangsu from 1 July 2014 to 31 December 2023, and RSV nucleic acid test was conducted and the intensity of the RSV infection was accessed by WHO influenza epidemiological threshold method, and case information and clinical data were collected. test was used to compare the differences between groups, and the Bonferroni method was used for pairwise comparisons between groups. In 4 946 cases of acute respiratory infections, the RSV positive rate was 8.21% (406/4 946), and the age (,) of the cases was 1 (0, 3) years. The RSV positive rate was 10.92% (258/2 362) during 2014-2019 and 6.06% (118/1 948) during 2019-2023, the difference was significant (=31.74, <0.001). RSV infection mainly occurred from October to March during 2014-2019, with the incidence peak in December and moderate or higher intensity. The seasonality of RSV infection was not obvious during 2019-2023, with low intensity. The RSV positive rate was highest in children in age group 0- years (17.85%, 151/846), and the positive rate declined gradually with age (=184.51, <0.001). The RSV positive rate was higher in inpatient cases (9.84%, 244/2 480) than in outpatient/emergency cases (6.57%, 162/2 466) (=17.54, <0.001). In the 155 RSV infection cases with complete clinical data, the clinical symptoms mainly included cough (99.35%, 154/155), fever (55.48%, 86/155), and shortness of breath (45.16%, 70/155). In the cases aged <6 months, the proportion of those with fever was low, but the proportion of those with shortness of breath, transferred to intensive care units, and receiving oxygen therapy were higher (all <0.05). Children aged <6 months and those with underlying diseases were more likely to have severe RSV infection (all <0.05). RSV infection in children in Jiangsu Province showed seasonal prevalence in winter from 2014 to 2019. Since 2020, the seasonal characteristics of the epidemic have changed, the epidemic period has been dispersed and the epidemic intensity has decreased. Infants <1 year old were at high risk for RSV infection, and those <6 months old and with underlying diseases might have severe infection.

Download full-text PDF

Source
http://dx.doi.org/10.3760/cma.j.cn112338-20240508-00251DOI Listing

Publication Analysis

Top Keywords

clinical characteristics
8
characteristics respiratory
8
respiratory syncytial
8
syncytial virus
8
children jiangsu
8
jiangsu province
8
rsv infection
8
acute respiratory
8
rsv positive
8
positive rate
8

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!