Research advances on the consolidated bioprocessing of lignocellulosic biomass.

Eng Microbiol

State Key Laboratory of Microbial Technology, Microbial Technology Institute, Shandong University, No.72 Binhai Road, Qingdao 266237, China.

Published: June 2024

AI Article Synopsis

  • *Consolidated bioprocessing (CBP) combines enzyme production, saccharification, and fermentation into one step using specific microbes, offering a more efficient approach to biomass conversion.
  • *The review discusses various CBP strategies, including natural, biosynthetic, and co-culturing microorganisms, and highlights innovative ways to utilize lignocellulosic biomass for producing valuable chemicals.

Article Abstract

Lignocellulosic biomass is an abundant and renewable bioresource for the production of biofuels and biochemical products. The classical biorefinery process for lignocellulosic degradation and conversion comprises three stages, i.e., pretreatment, enzymatic saccharification, and fermentation. However, the complicated pretreatment process, high cost of cellulase production, and insufficient production performance of fermentation strains have restricted the industrialization of biorefinery. Consolidated bioprocessing (CBP) technology combines the process of enzyme production, enzymatic saccharification, and fermentation in a single bioreactor using a specific microorganism or a consortium of microbes and represents another approach worth exploring for the production of chemicals from lignocellulosic biomass. The present review summarizes the progress made in research of CBP technology for lignocellulosic biomass conversion. In this review, different CBP strategies in lignocellulose biorefinery are reviewed, including CBP with natural lignocellulose-degrading microorganisms as the chassis, CBP with biosynthetic microorganisms as the chassis, and CBP with microbial co-culturing systems. This review provides new perspectives and insights on the utilization of low-cost feedstock lignocellulosic biomass for production of biochemicals.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11611046PMC
http://dx.doi.org/10.1016/j.engmic.2024.100139DOI Listing

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