A case report of non-classical treatment choice for mycosis fungoides (MF) presented on the left upper eyelid and forehead. Superficial brachytherapy using 3D technique was prescribed to preserve the lens's functionality, and successfully eliminate malignant lesion. Treatment was conducted with high-dose-rate (HDR) brachytherapy using iridium-192 (Ir) source as a base and Flexitron device as an afterloader. Applicators were immobilized and located near the lesion by manually shaped molds. Doses were calculated using Oncentra treatment planning system (ELEKTA) with 3D models based on CT scans. A 12-month follow-up showed sustained remission without any late toxicity or recurrence of MF skin lesions on the face. The proposed approach utilizing superficial, mold-based HDR brachytherapy to navigate anatomical challenges is demonstrated to be a clinically effective treatment option for MF of the lower eyelid or other dose-limiting locations.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11609854 | PMC |
http://dx.doi.org/10.5114/jcb.2024.143212 | DOI Listing |
Phys Imaging Radiat Oncol
October 2024
Division of Medical Physics, Department of Radiation Oncology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, German Cancer Consortium (DKTK), Partner Site DKTK, Freiburg, Germany.
J Contemp Brachytherapy
August 2024
Department of Oncology and Radiotherapy, University Clinical Centre in Gdan,sk, Gdan,sk, Poland.
Neurooncol Adv
September 2024
Department of Neurosurgery, Westchester Medical Center, Valhalla, New York, USA.
Background: GammaTile (GT), a form of brachytherapy utilizing cesium-131 seeds in a bioresorbable collagen tile, has gained popularity for the treatment of recurrent intracranial tumors and more recently for newly diagnosed metastases. This study reports early experience utilizing GT in upfront brain metastases with a focus on clinical applications and perioperative safety.
Methods: The STaRT Registry (NCT04427384) was queried for all patients receiving GT for upfront metastases from August 2021 to August 2023.
Cancer Radiother
November 2024
Department of Radiation Oncology, institut Curie, 26, rue d'Ulm, 75005 Paris, France; Université Versailles-Saint-Quentin, 78000 Versailles, France.
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