3D technique in superficial brachytherapy: New attitude in old field of mycosis fungoides.

J Contemp Brachytherapy

Department of Oncology and Radiotherapy, University Clinical Centre in Gdan,sk, Gdan,sk, Poland.

Published: August 2024

AI Article Synopsis

Article Abstract

A case report of non-classical treatment choice for mycosis fungoides (MF) presented on the left upper eyelid and forehead. Superficial brachytherapy using 3D technique was prescribed to preserve the lens's functionality, and successfully eliminate malignant lesion. Treatment was conducted with high-dose-rate (HDR) brachytherapy using iridium-192 (Ir) source as a base and Flexitron device as an afterloader. Applicators were immobilized and located near the lesion by manually shaped molds. Doses were calculated using Oncentra treatment planning system (ELEKTA) with 3D models based on CT scans. A 12-month follow-up showed sustained remission without any late toxicity or recurrence of MF skin lesions on the face. The proposed approach utilizing superficial, mold-based HDR brachytherapy to navigate anatomical challenges is demonstrated to be a clinically effective treatment option for MF of the lower eyelid or other dose-limiting locations.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11609854PMC
http://dx.doi.org/10.5114/jcb.2024.143212DOI Listing

Publication Analysis

Top Keywords

superficial brachytherapy
8
mycosis fungoides
8
hdr brachytherapy
8
technique superficial
4
brachytherapy
4
brachytherapy attitude
4
attitude field
4
field mycosis
4
fungoides case
4
case report
4

Similar Publications

On the impact of improved dose calculation accuracy in clinical treatment planning for superficial high-dose-rate brachytherapy of extensive scalp lesions.

Phys Imaging Radiat Oncol

October 2024

Division of Medical Physics, Department of Radiation Oncology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, German Cancer Consortium (DKTK), Partner Site DKTK, Freiburg, Germany.

Article Synopsis
  • TG-43 dose calculations in HDR brachytherapy often overlook variations in tissue density and scattering effects, leading to inaccuracies.
  • Model-based dose calculation algorithms (MBDCAs) were introduced to enhance precision in high-dose-rate (HDR) treatments, especially for extended scalp lesions.
  • This study found that MBDCAs provided more accurate dose estimations compared to TG-43, with discrepancies reduced to 2%-6% versus the 10%-23% overestimations seen with TG-43 at greater distances from the implant.
View Article and Find Full Text PDF
Article Synopsis
  • * The study involved five patients with inoperable tumors in different body locations, who received a total radiation dose of 51 Gy over 17 sessions, utilizing customized 3D-printed applicators.
  • * All patients achieved complete remission based on the RTOG scale, and post-treatment evaluations showed restored skin structure and notable healing, indicating the effectiveness of the tailored brachytherapy approach.
View Article and Find Full Text PDF

Background: GammaTile (GT), a form of brachytherapy utilizing cesium-131 seeds in a bioresorbable collagen tile, has gained popularity for the treatment of recurrent intracranial tumors and more recently for newly diagnosed metastases. This study reports early experience utilizing GT in upfront brain metastases with a focus on clinical applications and perioperative safety.

Methods: The STaRT Registry (NCT04427384) was queried for all patients receiving GT for upfront metastases from August 2021 to August 2023.

View Article and Find Full Text PDF

Electron radiation therapy: Back to the future?

Cancer Radiother

November 2024

Department of Radiation Oncology, institut Curie, 26, rue d'Ulm, 75005 Paris, France; Université Versailles-Saint-Quentin, 78000 Versailles, France.

Article Synopsis
  • Electron radiotherapy is preferred for treating superficial lesions due to its effectiveness at surface levels, but its complexity has led to a decline in use for many conditions, replaced by advanced techniques like intensity-modulated radiotherapy.
  • Though modern photon therapies are often chosen, they still fall short for certain specific conditions where electron therapy, including total skin irradiation and some pediatric treatments, remains superior.
  • The development of flash therapy, which offers high doses in a short time, shows promise with fewer side effects, indicating potential for new applications and a renewed interest in electron radiotherapy in specialized clinical settings.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!