Skin melanin lesions are typically identified as tiny patches on the skin, which are impacted by melanocyte cell overgrowth. The number of people with skin cancer is increasing worldwide. Accurate and timely skin cancer identification is critical to reduce the mortality rates. An incorrect diagnosis can be fatal to the patient. To tackle these issues, this article proposes the Recurrent Prototypical Object Segmentation Network (RPO-SegNet) for the segmentation of skin lesions and a hybrid Deep Learning (DL) - based skin cancer classification. The RPO-SegNet is formed by integrating the Recurrent Prototypical Networks (RP-Net), and Object Segmentation Networks (O-SegNet). At first, the input image is taken from a database and forwarded to image pre-processing. Then, the segmentation of skin lesions is accomplished using the proposed RPO-SegNet. After the segmentation, feature extraction is accomplished. Finally, skin cancer classification and detection are accomplished by employing the Fuzzy-based Shepard Convolutional Maxout Network (FSCMN) by combining the Deep Maxout Network (DMN), and Shepard Convolutional Neural Network (ShCNN). The established RPO-SegNet+FSCMN attained improved accuracy, True Negative Rate (TNR), True Positive Rate (TPR), dice coefficient, Jaccard coefficient, and segmentation analysis of 91.985%, 92.735%, 93.485%, 90.902%, 90.164%, and 91.734%.
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http://dx.doi.org/10.1080/0954898X.2024.2428705 | DOI Listing |
Oncologist
January 2025
Division of Hematology/Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, United States.
Immune checkpoint inhibitors (ICIs) have advanced the treatment of metastatic melanoma. However, some patients develop ICI-associated toxicities like hepatitis (ie, immune-mediated hepatitis; IMH). Although these toxicities usually resolve with steroids, steroid-refractory events may occur, which may be a major source of morbidity and mortality without obviously defined treatment algorithms.
View Article and Find Full Text PDFMelanoma is an aggressive type of skin cancer that arises from melanocytes, the cells responsible for producing skin pigment. In contrast to non-melanoma skin cancers like basal cell carcinoma and squamous cell carcinoma, melanoma is more invasive. Melanoma was distinguished by its rapid progression, high metastatic potential, and significant resistance to conventional therapies.
View Article and Find Full Text PDFCancer Cytopathol
February 2025
Photodermatol Photoimmunol Photomed
January 2025
Center for Preventive Medicine and Digital Health, CPD, Division of Public Health, Social and Preventive Medicine, Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany.
Background: Due to the global rise in UV radiation, the prevalence of skin cancer is increasing significantly, with outdoor athletes being identified as a particularly vulnerable population group.
Methods: This nationwide, cross-sectional study was conducted among adult coaches from the 10 largest outdoor sports associations in Germany. Their applied prevention measures and the potential for further improvement in prevention were evaluated by guideline based scores (range [0-100]).
Minerva Urol Nephrol
December 2024
European Association of Urology (EAU), Young Academic Urologists (YAU) Renal Cancer Working Group, Arnhem, the Netherlands.
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