Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1038/d41586-024-03918-w | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
RACK1 MARylation regulates translation and stress granules in ovarian cancer cells.
J Cell Biol
February 2025
Cecil H. and Ida Green Center for Reproductive Biology Sciences, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Mono(ADP-ribosyl)ation (MARylation) is emerging as a critical regulator of ribosome function and translation. Herein, we demonstrate that RACK1, an integral component of the ribosome, is MARylated by the mono(ADP-ribosyl) transferase (MART) PARP14 in ovarian cancer cells. MARylation of RACK1 is required for stress granule formation and promotes the colocalization of RACK1 in stress granules with G3BP1, eIF3η, and 40S ribosomal proteins.
View Article and Find Full Text PDFThe interstitial Ru dopant induces abundant Ni(Fe)Ru cooperative sites to promote ampere-level current density for overall water splitting.
J Colloid Interface Sci
February 2025
Key Laboratory of Eco-chemical Engineering, Ministry of Education, International Science and Technology Cooperation Base of Eco-chemical Engineering and Green Manufacturing, Qingdao University of Science and Technology, Qingdao, People's Republic of China; College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Key Laboratory of Optic-electric Sensing and Analytical Chemistry of Life Science, Taishan Scholar Advantage and Characteristic Discipline Team of Eco Chemical Process and Technology, Qingdao, People's Republic of China. Electronic address:
Article Synopsis
- - The study highlights the advantages of using interstitial Ru dopants over traditional substitutional doping, which enhances reaction rates for hydrogen and oxygen evolution reactions (HER and OER) by creating more active catalytic sites.
- - The researchers developed an interstitial Ru-doped NiFeP/NF electrode using a unique 'quenching doped Ru-phosphorization' method, resulting in improved electron dynamics and stability of the electrode during reactions.
- - Their findings demonstrate that this newly designed Ru-NiFeP/NF electrolyzer achieves a current density of 1 A/cm with a low voltage of just 1.54 V, suggesting a promising approach for optimizing Ru doping in electrocatalysis.
Light-driven synchronization of optogenetic clocks.
Elife
October 2024
Department of Physics, Sapienza University of Rome, Roma, Italy.
Synthetic genetic oscillators can serve as internal clocks within engineered cells to program periodic expression. However, cell-to-cell variability introduces a dispersion in the characteristics of these clocks that drives the population to complete desynchronization. Here, we introduce the optorepressilator, an optically controllable genetic clock that combines the repressilator, a three-node synthetic network in , with an optogenetic module enabling to reset, delay, or advance its phase using optical inputs.
View Article and Find Full Text PDFDrosophila require both green and UV wavelengths for sun orientation but lack a time-compensated sun compass.
J Exp Biol
October 2024
Graduate Neuroscience Program, University of California, Riverside, Riverside, CA 92521, USA.
Celestial orientation and navigation are performed by many organisms in contexts as diverse as migration, nest finding and straight-line orientation. The vinegar fly, Drosophila melanogaster, performs menotaxis in response to celestial cues during tethered flight and can disperse more than 10 km under field conditions. However, we still do not understand how spectral components of celestial cues and pauses in flight impact heading direction in flies.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!