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http://dx.doi.org/10.1016/j.ejim.2024.11.028 | DOI Listing |
J Surg Case Rep
January 2025
Department of Medical Affairs, Aroa Biosurgery Limited, 64 Richard Pearse Drive, Auckland 2022, New Zealand.
Pemphigus vulgaris (PV) is a subtype of pemphigus and life-altering disorder that results in the formation of intraepithelial blisters in mucosa and skin. Though the etiology is not well understood, it is an autoimmune disorder resulting in acantholytic blisters due to auto-antibodies targeting proteins of keratinocyte adhesion. Rapid diagnosis and restoration of the epidermal layer is imperative for patients with PV as widespread epidermal damage can lead to high morbidity and mortality rates.
View Article and Find Full Text PDFAn Bras Dermatol
January 2025
Dermatology Department, Dermatopathology, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Int J Surg Case Rep
January 2025
Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, Indonesia; Urology Department, Hasan Sadikin General Hospital, Bandung, West Java, Indonesia.
Introduction And Importance: Female urethral leiomyoma is a rare benign tumor that originates from the smooth muscle cells in the urethra's wall. Surgical resection is often the primary treatment option. However, the tumor's location and size can present challenges for complete removal while preserving urethral function.
View Article and Find Full Text PDFJ Dermatol
January 2025
School of Medicine, University of Crete, Heraklion, Greece.
Bullous pemphigoid (BP) is an autoimmune blistering disorder predominantly affecting the elderly. Recently, many studies have shed light on the effect of specific drug intake and comorbidities on the development of BP. The purpose of this study was to investigate the association of specific drug class intake and comorbidities with the development of BP in the Cretan population.
View Article and Find Full Text PDFFront Immunol
January 2025
Department of Dermatology, Jacobs School of Medicine and Biomedical Sciences, Buffalo, NY, United States.
Importance: Identifying environmental factors that contribute to disease onset/activity in PV stands to improve clinical outcomes and patient quality of life by strategies aimed at reducing specific disease promoting exposures and promoting personalized clinical management strategies.
Objective: To evaluate the association between hydroxychloroquine use and the development of pemphigus using population level, publicly available, FDA-generated data.
Design: Observational, retrospective, case-control, pharmacovigilance analysis.
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