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Multitracer PET/CT Findings in a Case of Behavioral Variant Frontotemporal Dementia With Parkinsonism. | LitMetric

We report the clinical and multimodal PET/CT manifestations in a patient with behavioral variant frontotemporal dementia and parkinsonism. The 18F-FDG PET scan revealed hypometabolism in the left supratentorial cortex. The 18F-fluorodopa PET scan demonstrated decreased uptake in the bilateral striatum, most prominent in the head of caudate nucleus. The 18F-florbetapir PET scan indicated an absence of β-amyloid deposition, whereas the 18F-flortaucipir PET scan showed uptake in the left hemisphere neocortex. The clinical presentation and asymmetric neuroimaging features supported the underlying frontotemporal lobar degeneration-tau pathology.

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http://dx.doi.org/10.1097/RLU.0000000000005611DOI Listing

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