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What Is Pink Cocaine? The Dark Reality behind a Colorful Name.
J Med Chem
December 2024
Vanderbilt University School of Medicine Basic Sciences, Warren Center for Neuroscience Drug Discovery, Franklin, Tennessee 37067, United States.
Clarifying the complex chemistry of cobalt(II) thiocyanate-based tests for cocaine using single-crystal X-ray diffraction and spectroscopic techniques.
J Forensic Sci
January 2024
Department of Chemistry and Chemical Engineering, Chalmers University of Technology, Gothenburg, Sweden.
Cobalt(II) thiocyanate-based tests are routinely used to screen cocaine products, with the formation of a blue species interpreted as a positive response. An array of other organic bases has been identified as false positives - including well-documented cocaine product adulterant lidocaine and its salt. False positives prompt continued test development, though improvements are hindered by unresolved product structures and reaction pathways.
View Article and Find Full Text PDFTusi: a new ketamine concoction complicating the drug landscape.
Am J Drug Alcohol Abuse
September 2023
Department of Population Health, New York University Grossman School of Medicine, New York, NY, USA.
A drug concoction called tusi has emerged in Latin America and in Europe and is now beginning to acquire popularity in the United States. "Tusi" is a phonetic translation of "2C," a series of psychedelic phenethylamines. The concoction is also sometimes referred to as "pink cocaine" as it typically comes in the form of pink powder.
View Article and Find Full Text PDFTemporal assessment of lesion morphology on radiological images beyond lesion volumes-a proof-of-principle study.
Eur Radiol
December 2022
Department of Radiology, Johns Hopkins University School of Medicine, 601 N Caroline St, Baltimore, MD, 21205, USA.
Objectives: To develop a general framework to assess temporal changes in lesion morphology on radiological images beyond volumetric changes and to test whether cocaine abstinence changes coronary plaque structure on serial coronary CT angiography (CTA).
Methods: Chronic cocaine users with human immunodeficiency virus (HIV) infection were prospectively enrolled to undergo cash-based contingency management to achieve cocaine abstinence. Participants underwent coronary CTA at baseline and 6 and 12 months following recruitment.
Identification of 2C-B in Hair by UHPLC-HRMS/MS. A Real Forensic Case.
Toxics
July 2021
Department of Chemistry and Drugs, National Institute of Toxicology and Forensic Sciences, Calle José Echegaray 4, Las Rozas de Madrid, 28232 Madrid, Spain.
The analysis of drugs of abuse in hair and other biological matrices of forensic interest requires great selectivity and sensitivity. This has been traditionally achieved through target analysis, using one or more analytical methods that include different preanalytical stages, and more complex procedures followed by toxicological laboratories. There is no exception with 2C-series drugs, such as 2C-B, a new psychoactive substance (NPS), which use has emerged and significantly increased, year by year, in the last decades.
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