Pullulan (PUL) is a widely used agent for electrospinning. However, nanofibers electrospun solely from PUL exhibit a highly hydrophilic nature and a bead-like structure. In this study, 1-5 wt% citrus pectin (CP) was introduced to construct a hybrid electrospinning system to investigate the effects of CP concentration on the properties of the electrospun nanofibers. The results reveal that the bead-like structure, rigidity, and hydrophobicity of the nanofibers underwent significant improvements following the introduction of CP. Furthermore, to demonstrate the protective effect of the nanofiber on astaxanthin, 0.1 wt% astaxanthin was encapsulated in the hybrid electrospinning system containing 5 wt% CP. The results show that after encapsulating astaxanthin, the rigidity of the nanofiber further increased, with a tensile strength of 12.5 MPa and a break elongation of 2.9 %. Additionally, the nanofiber system demonstrates excellent protection of the antioxidant activity of astaxanthin under UV exposure compared to free astaxanthin.
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http://dx.doi.org/10.1016/j.fochx.2024.101990 | DOI Listing |
Nanoscale Adv
December 2024
School of Engineering and Sciences, Tecnologico de Monterrey Monterrey 64849 Nuevo León Mexico
Liposomes are employed for the delivery of molecular cargo in several classes of systems. For instance, the embedding of loaded liposomes in polymeric fibrous scaffolds has enabled the creation of hybrid materials that mimic biological membranes. Liposomes with unmodified surfaces have been predominantly integrated into fibers, which leads to instabilities due to interfacial incompatibility.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
Department of Tissue Engineering and Regenerative Medicine, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences, Tehran, Iran.
Although tissue engineering science has made great progress, wound healing has remained a significant clinical challenge, especially in cases of severe injuries requiring advanced treatment strategies. This study aimed to develop patient-friendly in situ gelling nanofibers composed of oxidized carboxymethyl cellulose (OCMC) and gelatin for wound healing applications. A two-axial electrospinning technique was employed to fabricate OCMC/PVA-Gelatin hybrid nanofibers.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
Institute of Hybrid Materials, National Center of International Research for Hybrid Materials Technology, National Base of International Science & Technology Cooperation, College of Materials Science and Engineering, Qingdao University, Qingdao 266071, China. Electronic address:
Bacterial infections and excessive accumulation of wound exudates remain the main obstacles and clinical challenges to the healing of chronic cutaneous wounds. Conventional dressings are commonly used medical materials for acute wound care, but they do not possess the bacterial infection resistance required for chronic wound treatment. Herein, we prepared pure chitosan nanofibrous membranes (C) by electrospinning with poly(ethylene oxide) (PEO) as a sacrificial additive and then loaded with zinc-based metal-organic framework (MOF) as a novel antimicrobial wound dressing.
View Article and Find Full Text PDFDiscov Nano
January 2025
National Nanotechnology Laboratory for Agriculture (LNNA), Embrapa Instrumentação, 1452 XV de Novembro St., São Carlos, SP, 13560-970, Brazil.
Multifunctional membranes applied to biomedical materials become attractive to support the biological agents and increase their properties. In this study, biopolymeric fibers based on polycaprolactone (PCL) and pectin (PEC) were reinforced with faujasite zeolite (FAU) for cloxacillin antibiotic (CLX) loading. FAU with a high specific surface area (347 ± 8 m g), high crystallinity and particles with a diameter of up to 100 nm were produced under optimized synthesis conditions (100 °C/4 h).
View Article and Find Full Text PDFNanomaterials (Basel)
December 2024
College of Materials Science and Engineering, Jiangsu University of Science and Technology, Zhenjiang 212003, China.
The design and preparation of advanced hybrid nanofibers with controllable microstructures will be interesting because of their potential high-efficiency applications in the environmental and energy domains. In this paper, a simple and efficient strategy was developed for preparing hybrid nanofibers of zinc oxide-molybdenum disulfide (ZnO-MoS) grown on polyimide (PI) nanofibers by combining electrospinning, a high-pressure hydrothermal process, and in situ growth. Unlike simple composite nanoparticles, the structure is shown in PI-ZnO to be like the skeleton of a tree for the growth of MoS "leaves" as macro-materials with controlled microstructures.
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