AI Article Synopsis
- - Milk contamination, particularly from Shiga toxin-producing non-O157 STEC strains, poses significant public health risks, especially in areas like Kwara State, Nigeria, where data on this issue is limited.
- - The study examined 18 non-O157 STEC isolates from 1,225 milk samples, revealing four novel sequence types and five serotypes that carry various virulence and resistance factors.
- - Findings of this research underline the need for better hygiene in milk handling and inform public health policies to enhance food safety standards in the region.
Article Abstract
Background: is a major cause of poor microbial quality of milk, often resulting from unhygienic milk handling. Milk contamination poses public health concerns. Shiga toxin-producing (STEC) strains in food products, particularly milk, is a critical concern for public health. Limited information exists on the detection of non-O157 pathotypes in milk sold by local processors in Nigeria.
Aims: This study aimed to explore the diversity of non-O157 STEC isolates found in commercially available milk in Kwara State, Nigeria, to find the genetic diversity and potential risks associated with these strains.
Methods: A subgroup of 18 representative non-O157 STEC isolated from milk samples (n=1225) was selected for whole genome sequencing (WGS) analysis.
Results: Four novel sequence types (ST): ST398, ST540, ST1727, and ST9891 of non-O157 involving five serotypes: O176:H30, O176:H20, O8:H20, O21:H45, and O22:H7, carrying variable proportions of virulence factors, antimicrobial resistance genes, and plasmids, were identified.
Conclusion: This investigation contributes valuable data to the ongoing efforts to ensure food safety and prevent the transmission of strains through dairy products. The findings have implications for public health policies and food quality standards in Kwara State, Nigeria. Improved hygienic practices during milk handling are recommended.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11608529 | PMC |
| http://dx.doi.org/10.22099/IJVR.2024.49643.7307 | DOI Listing |
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