Background: Potassium levels play a significant role in cardiovascular patients, with hypokalemia and hyperkalemia having profound effects on the mortality rate. The aim of this study was to investigate the correlation of admission serum potassium levels and in-hospital mortality in patients suffering from acute ST-elevation myocardial infarction (STEMI).
Methods: The study was conducted in the Department of Cardiology, Ayub Teaching Hospital Abbottabad, and involved 225 patients with STEMI who underwent thrombolysis with streptokinase. The serum potassium levels of patients were recorded at the time of admission, and its correlation was observed with the short-term outcomes, i.e., discharge to home versus those who did not survive during the hospital stay of 72 hrs.
Results: The mean level of serum potassium at admission was 4.2 mmol/dL and 74.2% patients were discharged alive. T test indicated that a higher risk of death was associated with old age. No significant association between gender, serum potassium levels, systolic blood pressure, heart rate, and outcomes was seen. Logistic regression analysis further showed that age had a significant association with the outcome of death.
Conclusions: In our study, age had a significant impact on predicting the mortality of patients with STEMI and whereas the serum potassium levels at the time of admission did not exhibit any significant predictive value. Further research is needed to elucidate the complex interplay of various factors in predicting mortality, to improve the management practices of AMI.
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http://dx.doi.org/10.55519/JAMC-03-12114 | DOI Listing |
J Pak Med Assoc
January 2025
Department of Endocrinology, Bharti Hospital, Karnal, India; University Center for Research & Development, Chandigarh University, Mohali, India.
Hyperkalaemia is a life-threatening dyselectrolytaemia which is characterized by elevated serum potassium levels. It needs a systematic and overarching approach to effectively manage a case of hyperkalaemia. We propose a structured A-to-H approach to guide clinicians in managing hyperkalaemia, ensuring that no critical aspect is neglected or inadvertently missed.
View Article and Find Full Text PDFBMJ Case Rep
January 2025
Neonatology, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Sulfasalazine is a non-specific immunomodulator with haemolytic anaemia as a known side effect that crosses the placenta. We present a preterm neonate with cardiac arrhythmia secondary to hyperkalaemia in the setting of maternal sulfasalazine therapy. A preterm infant was born to a mother taking hydroxychloroquine, sulfasalazine, aspirin and enoxaparin throughout pregnancy.
View Article and Find Full Text PDFJ Clin Hypertens (Greenwich)
January 2025
Department of Nephrology, Southeast University Zhongda Hospital, Southeast University School of Medicine, Nanjing, China.
To assess the effectiveness and safety of Sacubitril/Valsartan in reducing blood pressure in individuals with non-dialysis-dependent chronic kidney disease (NDD-CKD) Stage 3-5 complicated by hypertension. This study was a multicenter retrospective analysis conducted from March 1, 2022 to March 31, 2024, involving adult patients with NDD-CKD Stage 3-5 and hypertension, who received Sacubitril/Valsartan either as a monotherapy or in addition to current antihypertensive treatments that were insufficient. The main outcomes measured were blood pressure control, changes in blood pressure and laboratory parameters within 8 weeks post-treatment initiation, and incidence of adverse events.
View Article and Find Full Text PDFClin Exp Nephrol
January 2025
Internal Medicine Department, El Qabbary General Hospital, Ministry of Health, Alexandria, Egypt.
Background: Oral nutritional supplements (ONS) are commonly prescribed to provide protein and energy to hemodialysis (HD) patients. There is a debate about the appropriate timing to administer ONS. We aimed to study the effect of different timings of ONS on variable outcomes in HD patients.
View Article and Find Full Text PDFKidney360
January 2025
Center for Cardiac Arrest Prevention, Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Health System, Los Angeles, CA, United States.
Background: Individuals with end-stage renal disease may be at increased risk of sudden cardiac arrest (SCA) associated with dialysis therapy. However, community-based studies with comprehensive adjudication of SCA are lacking.
Methods: We conducted a community-based study using a case-case study design in a US population of ≈1 million.
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