AI Article Synopsis
- A study evaluated the correlation between the optic nerve sheath diameter (ONSD) measured via ultrasound and the opening pressure (OP) of cerebrospinal fluid (CSF) in patients diagnosed with idiopathic intracranial hypertension (IIH), highlighting ONSD as a non-invasive alternative to traditional lumbar puncture.
- Conducted from June 2021 to May 2023, the study included 50 participants (25 with IIH and 25 controls), comparing their ONSD and OP measurements to establish a relationship.
- Results showed that a mean ONSD of 5.60 mm can effectively indicate raised intracranial pressure with high sensitivity and specificity, suggesting its use as a reliable, non-invasive assessment tool
Article Abstract
Background: Evaluation of opening pressure (OP) of CSF on lumbar puncture (LP) is an invasive procedure for the confirmation of diagnosis of idiopathic intracranial hypertension (IIH). Sonographic optic nerve sheath diameter (ONSD) measurement is a non-invasive method which can help in the estimation of intracranial pressure (ICP). The study was carried out to find out the correlation between ONSD and OP on LP in patients of IIH.
Methods: The Cross-sectional study was hosted by medical teaching institute, Gajju Medical College, Swabi and Frontier institute of Ophthalmology, Peshawar, from 1st June, 2021 to 31st May, 2023.Total participants were 50, 25 in Group A having diagnosis of IIH and 25 in Group B as control group from general population. The patients in Group A had ONSD assessment followed by measurement of OP and then the process was repeated at two weeks follow up. Participants in Group B had only one assessment of ONSD. Correlation between ONSD and OP was determined. Best cut-off-value for raised ICP was calculated.
Results: The mean ONSD was 5.91±0.63 in Group A and 5.07±0.50 in Group B (p=0.00). The mean OP in Group A was 31.64±3.81 cm H2O initially. The mean ONSD and OP at follow up were 5.18±0.42 and 19.64±3.52 cm H2O respectively. The best cut-off-value was 5.60 mm of ONSD for estimation of raised ICP (sensitivity 88% and specificity 88%).
Conclusions: Sonographic ONSD has a positive correlation with OP on LP in IIH patients and can be used as a non-invasive tool for the assessment of ICP in IIH patients.
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| http://dx.doi.org/10.55519/JAMC-03-12890 | DOI Listing |
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