[Current status of treatment for acute variceal bleeding in liver cirrhosis].

Zhonghua Gan Zang Bing Za Zhi

Xijing Hospital of Digestive Diseases, Air Force Medical University, Xi'an710032, China.

Published: November 2024

AI Article Synopsis

  • Acute variceal bleeding (AVB) remains a serious complication of cirrhotic portal hypertension, with a hospitalization rate declining due to advanced medical technology, yet in-hospital mortality rates still range from 0% to 32% depending on cirrhosis severity.
  • The overall mortality from AVB has improved significantly, dropping from 50% to 15%-20% over the past thirty years.
  • The article emphasizes the importance of risk stratification and individualized treatment for AVB patients, given the varied risk of death based on the severity of cirrhosis.

Article Abstract

Acute variceal bleeding (AVB) continues to be a fatal complications of cirrhotic portal hypertension. Although the hospitalization rate of patients with acute variceal bleeding has significantly decreased with the advancement of medical technology, and the mortality rate has dropped from 50% three decades before to 15%~20% now, the in-hospital mortality rate is still high and is closely related to the severity of cirrhosis, ranging from 0 in Child A grade to 32% in Child C grade. Therefore, it is a good choice to risk stratify these patients and individualize the treatment method according to the expected risk, as the risk of death in patients with acute variceal bleeding is highly heterogeneous. This article mainly reviews the current status of risk stratification and treatment of acute variceal bleeding in cirrhosis.

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Source
http://dx.doi.org/10.3760/cma.j.cn501113-20240306-00113DOI Listing

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