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Prevalence, risk factors, and severity of erectile dysfunction following renal transplantation. | LitMetric

AI Article Synopsis

  • - The study examined erectile dysfunction (ED) among male kidney transplant recipients, finding that 33.5% had mild, 20.6% moderate, and 10.6% severe ED, with prevalence increasing with age.
  • - A total of 179 patients were assessed using the International Index of Erectile Function (IIEF) questionnaire, which revealed a mean erectile function score of 19.22 and highlighted the impact of various factors like age, alcohol consumption, and pre-transplant dialysis on ED.
  • - The research concluded that self-reported ED is significantly influenced by age, alcohol intake, dialysis history, donor type, and specific medications, while comorbidities such as hypertension and diabetes did not show a

Article Abstract

Background: Sexual dysfunction is common among dialysis and transplant patients. Our study evaluated the prevalence, risk factors, and severity of erectile dysfunction (ED) post-transplant in a single center.

Methods: We conducted a single-centre, observational, non-interventional study of adult male renal graft recipients. Sociodemographic and clinical data were collected, and erectile function was assessed with the International Index of Erectile Function (IIEF) questionnaire.

Results: 179 patients transplanted between 1995 and 2021 were enrolled (170 answered the questionnaire). Mild, moderate, and severe ED was noted in 33.5%, 20.6% and 10.6% of cases, respectively. ED prevalence increased with age (42.6% of patients < 40, 47.4% of patients aged 40-60, 78.9% of patients > 60). The total mean IIEF score was 16.32 ± 6.93 (erectile function 19.22 ± 7.9, orgasmic function 6.8 ± 2.9, sexual desire 6.43 ± 2.1, intercourse satisfaction 8.96 ± 3.7, overall satisfaction 6.78 ± 2.6). Age, alcohol consumption, type, time on dialysis pre-transplant, and donor type were significantly associated with erectile dysfunction (p < 0.05). Most patients (93.5%) were treated for comorbidities in addition to immunosuppression. Severe ED was significantly more common among patients taking alpha blockers and non-steroidal anti-inflammatory drugs.

Conclusions: Self-reported erectile dysfunction post renal transplantation seems influenced by age, alcohol intake, dialysis history, donor type and certain drugs, but not by comorbidities (hypertension, diabetes, heart disease).

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Source
http://dx.doi.org/10.1007/s11255-024-04299-9DOI Listing

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