AI Article Synopsis

  • Large language models can capture changes in how words are understood in people with mental disorders by analyzing their semantic space, particularly looking at how word meanings relate.
  • Recent studies show a 'shrinking' semantic space in psychosis, where words tend to be more similar to each other in meaning.
  • In a study comparing patients with schizophrenia spectrum disorders and major depression to healthy controls, both clinical groups exhibited more restricted ways of navigating meaning, indicating changes in how they connect ideas compared to those without mental health issues.

Article Abstract

Large language models provide high-dimensional representations (embeddings) of word meaning, which allow quantifying changes in the geometry of the semantic space in mental disorders. A pattern of a more condensed ('shrinking') semantic space marked by an increase in mean semantic similarity between words has been recently documented in psychosis across several languages. We aimed to explore this pattern further in picture descriptions provided by a transdiagnostic German sample of patients with schizophrenia spectrum disorders (SSD) (n = 42), major depression (MDD, n = 43), and healthy controls (n = 44). Compared to controls, both clinical groups showed more restricted dynamic navigational patterns as captured by the time series of semantic distances crossed, while also showing differential patterns in the total distances and trajectories navigated. These findings demonstrate alterations centred on the dynamics of the flow of meaning across the semantic space in SSD and MDD, preserving previous indications towards a shrinking semantic space in both cases.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11612388PMC
http://dx.doi.org/10.1038/s41537-024-00524-7DOI Listing

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