AI Article Synopsis

  • Cannabidiol (CBD) is a cannabis compound with potential medical benefits, and this study aimed to assess its usage among patients in substance use disorder treatment.
  • Out of 183 patients, 38.2% reported using CBD in the past year, but 63% had recently stopped, mainly due to ineffectiveness and cost concerns.
  • CBD users tend to be younger with psychiatric comorbidities and prefer inhalation methods, and the study highlights the importance for clinicians to regularly ask about CBD use due to potential drug interactions.

Article Abstract

Introduction: Cannabidiol (CBD) is one of the two primary phytocannabinoids found in cannabis. Its diverse pharmacological properties suggest potential benefits for a wide range of medical conditions. The primary objective of this study was to estimate the prevalence of CBD use among patients being treated for substance use disorder. Additionally, we aimed to characterize the pattern of CBD use and describe the profiles of users.

Methods: Patients admitted to two substance use disorder departments between May 6, 2020, and July 23, 2021, were included in the study. Sociodemographic, medical and substance use data, including CBD use, were collected. A multiple correspondence analysis (MCA) was performed to identify substance uses most frequently correlated with CBD use. Multivariate analyses were also conducted to identify factors associated with CBD use.

Results: The prevalence of CBD use in the past 12 months among the 183 patients was 38.2%. However, at the time of the study, 63% had stopped using CBD, primarily due to its perceived ineffectiveness and cost. CBD was commonly consumed via inhalation, either by smoking the plant or using e-cigarette liquids. The MCA revealed that while there is no typical profile of CBD users, they were more likely to use sedative substances rather than stimulants. CBD users were younger and more likely to have psychiatric comorbidities.

Conclusion: The prevalence of CBD use was notably high. Given the significant risk of drug interactions with CBD and its wide variability in composition, it is crucial for clinicians to routinely inquire about CBD use. The potential for self-therapeutic or recreational use in these patients appears to be underestimated.

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http://dx.doi.org/10.1159/000541887DOI Listing

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