Background: Unexpected events such as instrument breakage during a routine lumbar microdiscectomy can pose a risk for nerve root injury, durotomy, infection, and anterior displacement into the retroperitoneal space. Removal of broken instruments requires planning, patience, and sometimes subsequent surgical procedures. Here, the authors explore the effectiveness of a magnetic probe for the retrieval of broken metallic (magnetic) pieces.
Observations: A 47-year-old man with right leg radiculopathy due to a right L5-S1 disc extrusion had undergone a lumbar microdiscectomy that was complicated by the pituitary rongeur tip breaking in the L5-S1 disc space. The rongeur tip was successfully retrieved by widening the entry access without damaging the adjoining facet and utilizing a blunt nerve hook, a probe dissector, forceps tips, curette heads, and a magnetic probe.
Lessons: The use of a magnetic probe provides a safe and effective method for retrieving metallic fragments during lumbar disc surgery. This case highlights the importance of considering alternative techniques such as magnetic retrieval in the management of intraoperative instrument breakage. https://thejns.org/doi/10.3171/CASE24377.
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http://dx.doi.org/10.3171/CASE24377 | DOI Listing |
Spectrochim Acta A Mol Biomol Spectrosc
December 2024
School of Agriculture and Bioengineering, Heze University, Heze 274500, China. Electronic address:
Herin, the successful synthesis of a bis Schiff base (L) has been achieved using 2-hydroxy-1-naphthaldehyde and 1,3-diaminoguanidine as raw materials, which was further characterized by infrared spectroscopy, mass spectrometry, and nuclear magnetic resonance hydrogen spectrum. Moreover, spectroscopic experiments demonstrated that the probe L showed good selectivity and visual detectability for Al. Its detection limit (DL) is 2.
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International Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China; Ministry of Education Key Laboratory for Animal Pathogens and Biosafety, College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China. Electronic address:
African swine fever has caused huge losses to the global pig industry. In the absence of effective vaccines, reliable detection methods are crucial. The p30 protein of ASFV is often used as a target for detection due to its high antigenicity in the early stage of virus replication.
View Article and Find Full Text PDFBiosens Bioelectron
December 2024
School of Materials Science and Chemical Engineering, Ningbo University, Ningbo, Zhejiang, 315200, China. Electronic address:
Routine screening for cardiovascular diseases (CVDs) through point-of-care assays for at-home or community-based testing of salivary biomarkers can significantly improve patient outcomes. However, its translatability has been hindered by a dearth of biosensing devices that streamline assay procedures for rapid biomarker quantitation. To address this challenge through end-to-end engineering, we developed an in-house, all-in-one microfluidic immunosensing device that integrates on-chip vibration-enhanced incubation, magnetic-assisted separation using immune magnetic bead probes, and colorimetric readout via absorbance measurements.
View Article and Find Full Text PDFJ Eat Disord
December 2024
Centre for Neuroscience Studies, Queen's University, Kingston, ON, Canada.
Eating disorders (EDs) are a group of debilitating mental illnesses characterized by maladaptive eating behaviors and severe cognitive-emotional dysfunction, directly affecting 1-3% of the population. Standard treatments are not effective in approximately one third of ED cases, representing the need for scientific advancement. There is emerging evidence for the safety and efficacy of psilocybin-assisted psychotherapy (PAP) to improve treatment outcomes in individuals with EDs.
View Article and Find Full Text PDFChemistry
December 2024
CNRS, Centre de Biophysique Moléculaire, Rue Charles Sadron, 45071, Orléans, FRANCE.
Zinc is an important physiological cation, and its misregulation is implicated in various diseases. It is therefore important to be able to image zinc by non-invasive methods such as Magnetic Resonance Imaging (MRI). In this work, we have successfully synthesized a novel Gd3+-based complex specifically for Zn2+ sensing by MRI.
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