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Interaction between bacterial adhesins leads to coaggregation by the oral bacteria and .
mBio
January 2025
Antimicrobial Resistance, Omics and Microbiota Group, Centre for Systems Health and Integrated Metabolic Research, Department of Biosciences, Nottingham Trent University, Nottingham, United Kingdom.
is an unusual diderm firmicute that plays a central role in the formation of dental biofilm formation through coaggregation with many other oral bacteria. However, the molecular interactions leading to oral biofilm formation are largely unknown. In a recent study (L.
View Article and Find Full Text PDFBrain aging and rejuvenation at single-cell resolution.
Neuron
January 2025
Department of Genetics, Stanford University, Stanford, CA, USA; Glenn Center for the Biology of Aging, Stanford University, Stanford, CA, USA; Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA, USA. Electronic address:
Brain aging leads to a decline in cognitive function and a concomitant increase in the susceptibility to neurodegenerative diseases such as Alzheimer's and Parkinson's diseases. A key question is how changes within individual cells of the brain give rise to age-related dysfunction. Developments in single-cell "omics" technologies, such as single-cell transcriptomics, have facilitated high-dimensional profiling of individual cells.
View Article and Find Full Text PDFSingle-Cell Lineage Tracing and Clonal State-Fate Analysis.
Methods Mol Biol
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Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Catalonia, Spain.
Lineage tracing has significantly advanced our comprehension in many areas of biology, such as development or immunity, by precisely measuring cellular processes like migration, division, or differentiation across labeled cells and their progeny. Traditional recombinase-based prospective lineage tracing is limited by the need for a priori cell type information and is constrained in the numbers of clones it can simultaneously track. In this sense, clonal lineage tracing with integrated random barcodes offers a robust alternative, enabling researchers to label and track a vast array of cells and their progeny over time.
View Article and Find Full Text PDFConcise Recommendations for EDitorials: Enhancing Narratives and Composition Effectively (CREDENCE).
J Korean Med Sci
December 2024
Division of Musculoskeletal and Dermatological Sciences, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.
An editorial article is a type of scholarly communication providing expert views and critical analysis of issues. It may reflect the view of the author(s) or of the organization/journal on a certain topic. An editorial may also comment on a published paper.
View Article and Find Full Text PDFImportance of the Hemoglobin Glycation Index for Risk of Cardiovascular and Microvascular Complications and Mortality in Individuals with Type 2 Diabetes (Endocrinol Metab 2024;39:732-47, Claudia Regina Lopes Cardoso et al.).
Endocrinol Metab (Seoul)
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Department of Internal Medicine, University Hospital Clementino Fraga Filho, School of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
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