Background: Relative Energy Deficiency in Sport (REDs) is a serious clinical condition. However, there is little research in athletes with a clinical diagnosis and limited evidence on the recovery of REDs.
Methods: This is a cross-sectional retrospective study whereby 55 (25.62±6.33 years) female patients with a prior diagnosis of REDs by an experienced medical specialist participated in an online questionnaire designed to capture their experience of a sports dietitian consultation and subsequent implementation of a personalized energy availability (EA) plan.
Results: A 31% increase (N.=4 vs. N.=16, P=0.002) in normal menstruation, a 22% reduction (N.=39 vs. N.=27, P=0.032) in gastrointestinal symptoms, and a 94% reduction (N.=16 to N.=1) in a very poor/poor appetite were reported following the consultation and plan implementation. Required energy intake (EI) was under-estimated by 93% of participants. Intake pre-exercise was implemented most frequently (69%, N.=38), and least likely to elicit feelings of stress and anxiety (69%, N.=38). Weight gain/shape change was the most frequently reported barrier to implementation (62%, N.=34). Eating to a planned regime (35%, N.=19) and following a timing of intake (33%, N.=18) gave the most confidence.
Conclusions: Providing an athlete with an education of their current and required EA, alongside an illustrated personalized EI plan structured around exercise, may provide the "lightbulb" moment needed to overcome the associated anxiety when increasing their EI when recovering from REDs.
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http://dx.doi.org/10.23736/S0022-4707.24.15942-7 | DOI Listing |
Plant Physiol
January 2025
Institute of Biology, University of Graz, Graz, Austria.
Understanding the molecular mechanisms of abiotic stress responses in plants is instrumental for the development of climate-resilient crops. Key factors in abiotic stress responses, such as the proton- pumping pyrophosphatase (AVP1), have been identified, but their function and regulation remain elusive. Here, we explored the post-translational regulation of AVP1 by the ubiquitin-conjugating enzyme UBC34 and its relevance in the salt stress and phosphate starvation responses of Arabidopsis (Arabidopsis thaliana).
View Article and Find Full Text PDFOrg Lett
January 2025
Key Laboratory of Material Chemistry for Energy Conversion and Storage, Ministry of Education, Hubei Key Laboratory of Bioinorganic Chemistry and Materia Medica, Hubei Engineering Research Center for Biomaterials and Medical Protective Materials, School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, 1037 Luoyu Road, Wuhan 430074, China.
Herein, we report an approach for the synthesis of 2-sulfonyl carbazoles from the oxidative C-H sulfonylation of tetrahydrocarbazoles. The mechanistic study reveals that this special selectivity is realized by the addition of a sulfonyl radical to the 3,4-dihydrocabazole intermediate via dehydrogenative desaturation of tetrahydrocarbazoles. This approach features readily available starting materials, high regioselectivity, broad substrate scope, and attractive synthetic utility.
View Article and Find Full Text PDFAcc Chem Res
January 2025
Center for Molecular Spectroscopy and Dynamics, Institute for Basic Science, Seoul 02841, Korea.
ConspectusWater-in-salt electrolytes (WiSEs) are promising electrolytes for next-generation lithium-ion batteries (LIBs), offering critical advantages like nonflammability and improved safety. These electrolytes have extremely high salt concentrations and exhibit unique solvation structures and transport mechanisms dominated by the formation of ion networks and aggregates. These ion networks are central to the performance of WiSEs, govern the transport properties and stability of the electrolyte, deviating from conventional dilute aqueous or organic electrolytes.
View Article and Find Full Text PDFNucleic Acids Res
January 2025
SynVaccine Ltd, Ramat Hachayal, 3 Golda Meir Street, Science Park, Nes Ziona 7403648, Israel.
Many viruses of the Flaviviridae family, including the Zika virus (ZIKV), are human pathogens of significant public health concerns. Despite extensive research, there are currently no approved vaccines available for ZIKV and specifically no live-attenuated Zika vaccine. In this current study, we suggest a novel computational algorithm for generating live-attenuated vaccines via the introduction of silent mutation into regions that undergo selection for strong or weak local RNA folding or into regions that exhibit medium levels of sequence conservation.
View Article and Find Full Text PDFJ Clin Med
January 2025
Department of Orthopaedic Surgery, CHA Bundang Medical Center, CHA University School of Medicine, 335 Pangyo-ro, Bundang-gu, Seongnam-si 13488, Gyeonggi-do, Republic of Korea.
: With the rapid increase in the aging population, the number of patients complaining of shoulder pain is also increasing. Among shoulder ailments, rotator cuff tears (RCTs) are most frequently observed in middle-aged and elderly individuals. Sarcopenia refers to the decline in muscle mass (lean body mass) and the subsequent decrease in muscle function that is linked to the natural aging process.
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