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Effects of Atropine on Choroidal Hemodynamics and VEGFA and HIF-1α Expression in Form-Deprivation Myopia Guinea Pigs.
Exp Eye Res
December 2024
Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; College of Health Science and Technology, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address:
We investigated the mechanism of action of atropine in myopia control by examining its effect on choroidal hemodynamics. Blood flow was evaluated using indocyanine green (ICG) fluorescence and molecular variation during the development of form-deprivation myopia (FDM) and atropine treatment in guinea pigs. Guinea pigs were divided randomly into the normal control (NC), FDM, and FDM + 1% atropine (ATR) groups, and evaluated by spherical equivalent refractive error (SE) and axial length (AL).
View Article and Find Full Text PDFDynamics of Myopia Progression in Ghana-Evidence From Clinical Practice: A Retrospective Cohort Study.
Health Sci Rep
December 2024
Optometry Unit, Department of Clinical Surgical Sciences, Faculty of Medical Sciences The University of the West Indies, St. Augustine St. Augustine Trinidad and Tobago.
Background And Aim: To investigate the pattern of progression of myopia among a Ghanaian clinical cohort.
Methods: A retrospective cohort analysis of a clinical data set of all healthy myopic participants attending a tertiary eye care center was performed. Participants' biennial refraction examinations were tracked for refractive changes 4 years after the date of the first visit.
Corneal protein repair after amniotic membrane photo-tissue bonding versus amniotic membrane graft in the treatment of corneal ulcer (an experimental study).
Sci Rep
December 2024
Department of Medical Application of Laser, Ophthalmic Unit, National Institute of Laser Enhanced Sciences, Cairo University, Giza, Egypt.
Corneal alkali burns persist as a significant challenge in our field, often leading to a prolonged treatment course with various sight-threatening problems. This work, of utmost importance, aimed to apply the photo-tissue bonding technique (PTB) to weld the amniotic membrane (AM) to the corneal surface versus an amniotic membrane graft (AMG) and explore its safety in saving corneal protein against alkali burn.Methods Twenty-seven rabbits with an induced corneal ulcer using 1 mol/L NaOH solution.
View Article and Find Full Text PDFRefractive change at 5 years in the Toddler Aphakia and Pseudophakia Study (TAPS).
Ophthalmology
December 2024
Department of Ophthalmology, Mayo Clinic, Rochester, MN; Department of Ophthalmology and Visual Neurosciences, Minneapolis, University of Minnesota, MN;. Electronic address:
Article Synopsis
- The study focuses on refractive changes observed in children aged 5 years who underwent cataract surgery with intraocular lens placement before age 2.
- It analyzed data from 96 children, comparing results between unilateral and bilateral cataract cases, as well as those operated on at different ages (1 to <7 months vs. 7-24 months).
- The findings indicated that children operated on between 1 to <7 months experienced significantly more refractive change compared to those operated on later, suggesting careful consideration is needed when selecting lens power and target refraction for younger patients.
THERAPEUTIC REFRACTIVE VITRECTOMY (TRV) FOR THE MANAGEMENT OF VITREOUS FLOATERS AND OPACITIES (VFO) ASSESSED BY THE STANDARDIZED AND KINETIC ANATOMICAL AND FUNCTIONAL TESTING OF VITREOUS FLOATERS AND OPACITIES (SK VFO TEST).
Retina
December 2024
The Retina Clinic London, 140 Harley Street, London W1G 7LB, United Kingdom.
Purpose: Propose new terminology and evaluate the effectiveness of Therapeutic Refractive Vitrectomy (TRV) for selective removal of vitreous floaters and opacities (VFO) utilizing Standardized Kinetic Anatomical Functional Testing of VFO (SK VFO Test) and new ultra widefield (UWF) OCT imaging techniques.
Methods: Retrospective analysis. Twenty eyes underwent TRV for symptomatic VFO.
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