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An Unusual Case of Adrenocortical Carcinoma with Multiple Facets. | LitMetric

An Unusual Case of Adrenocortical Carcinoma with Multiple Facets.

J ASEAN Fed Endocr Soc

Pathology Department, Sarawak General Hospital, Ministry of Health, Malaysia.

Published: December 2024

AI Article Synopsis

  • Adrenocortical carcinoma (ACC) is a rare cancer originating from the adrenal cortex, with about half of the cases being functional and producing excess cortisol.
  • It is unusual for ACC to show high metanephrine levels, which are typically seen in pheochromocytoma.
  • A case study is presented of a large adrenal tumor displaying characteristics of both ACC and pheochromocytoma, ultimately diagnosed as metastatic ACC through biopsy.

Article Abstract

Adrenocortical carcinoma (ACC) is a rare malignant tumour from the adrenal cortex. Half of the cases are functional, with ACTH-independent autonomous cortisol production being the most common. It is rare for ACC to present with markedly elevated metanephrine levels, characteristic of pheochromocytoma. We report a case of a large functioning adrenal tumour with overlapping biochemical features of ACC and pheochromocytoma. Biopsy confirmed the histopathological diagnosis of metastatic ACC.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11604357PMC
http://dx.doi.org/10.15605/jafes.039.02.16DOI Listing

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