Children's autonomy includes, as far as possible, self-determination, bodily integrity and the right to influence outcomes. Limits to bodily integrity, which involves no touching without the child's consent or tacit agreement, are discussed. The clinical, legal and ethics literature tends to agree that children may give valid consent to major recommended treatment from around 12 years but may not refuse it until they are legal adults. Research shows that young children are more aware of their bodily integrity and autonomy, of morality and decision making, than was assumed in the past. Adults therefore need to inform children and respect their initially instinctive efforts to protect their bodily integrity. Unlike assent, consent involves patients being adequately informed and being able to accept or refuse proposed treatment. Reasons are given for adults' need to consult with children when determining their best interests. Beyond words, giving or withholding consent also involves emotions of fear, trust and courage, besides embodied reactions of cooperating with treatment or resisting it, in which young children actively engage. Some clinicians work with the informed cooperation of young children who need lifesaving treatment, and at times accept their refusal. Reasons for differences between mainstream experts' views and clinical practices are considered.
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http://dx.doi.org/10.1177/14777509231188006 | DOI Listing |
Front Cell Dev Biol
December 2024
Department of Biochemistry, Memorial University of Newfoundland, St. John's, NL, Canada.
PIWI-interacting RNAs (piRNAs) are small non-coding RNAs that bind to the PIWI subclass of the Argonaute protein family and are essential for maintaining germline integrity. Initially discovered in , PIWI proteins safeguard piRNAs, forming ribonucleoprotein (RNP) complexes, crucial for regulating gene expression and genome stability, by suppressing transposable elements (TEs). Recent insights revealed that piRNAs and PIWI proteins, known for their roles in germline maintenance, significantly influence mRNA stability, translation and retrotransposon silencing in both stem cells and bodily tissues.
View Article and Find Full Text PDFNeuroscience
December 2024
University of Debrecen, Hungary. Electronic address:
Surgeries are situations that endanger bodily integrity. The concept expressed by the term coined by Sherrington encompasses the perception of noxious stimuli and the organization of response to them. To understand the condition of the brain in which anesthesia is performed it is important to review new results of the neurophysiology of nociception.
View Article and Find Full Text PDFInt J Legal Med
December 2024
Department of Forensic Science, School of Basic Medical Sciences, Central South University, No. 172 Tongzipo Road, Changsha, Hunan Province, 410013, PR China.
In forensic practice, identifying the species of unknown bodily fluid stains can provide assistance in the qualitative analysis and investigation of cases, and vaginal fluid stains, as one of the common bodily fluid stains, are most commonly seen at the scene of sexual assault. At present, the commonly used vaginal peptidase or microscopic detection methods currently have drawbacks such as high false negative rates, poor sensitivity, and high requirements for sample integrity and background color. However, in forensic investigations, the test materials have specificity and scarcity, making it difficult to ensure their quantity and quality.
View Article and Find Full Text PDFClin Ethics
December 2024
Social Research Institute, University College London, London, UK.
Children's autonomy includes, as far as possible, self-determination, bodily integrity and the right to influence outcomes. Limits to bodily integrity, which involves no touching without the child's consent or tacit agreement, are discussed. The clinical, legal and ethics literature tends to agree that children may give valid consent to major recommended treatment from around 12 years but may not refuse it until they are legal adults.
View Article and Find Full Text PDFBioethics
November 2024
Department of Public Health, University of Copenhagen, København, Denmark.
The growing demand for uterus transplantation (UTx) invites continued philosophical evaluation of the function of UTx (and what constitutes its 'success'), as well as the recipient eligibility for UTx. Currently, UTx caters to partnered, cisgender women of childbearing age looking to get pregnant and give birth to a biogenetically related child. The medical justification for this-the treatment of uterine infertility-explains the primacy of this practice.
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