Background: This study seeks to define the pulmonary function of a considerably large group in one of the largest automotive companies in Iran. The aim of this study was to compare the two groups of spot-welding (exposed) and assembly line (unexposed) workers in terms of pulmonary function and conclude the probable impacts of metal fumes on pulmonary function in the two groups.
Methods: A total of 1,798 spot-welding personnel and 2,160 assembly line personnel were compared in terms of pulmonary function. Moreover, 120 breathing zone samples were collected from the welders' metal fumes and were analyzed. The parameters of age, anthropometric indices, smoking, and pulmonary symptoms were also compared with across the two groups.
Results: Results revealed the FEV mean of the total population to be 3.9 ± 0.5 liters and FVC to have been 4.9 ± 0.7 liters. Besides, predicted FEV and FVC percentages across the whole population were close to 100%, suggesting the better condition of the studied population compared with normal individuals in the society. All the parameters of age, weight, height, and smoking status were similar in the two groups, and no statistically significant difference was observed between the two groups in terms of pulmonary functions.
Conclusion: Implementation of professional health and health improvement programs, running screening programs, and hiring personnel with no history of mild pulmonary disorders, and healthy workers effect at the recruitment stage could be the reasons behind the lack of significant difference between the two exposed and unexposed groups to metal fumes in the automotive industry in terms of pulmonary function.
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http://dx.doi.org/10.4103/ijoem.ijoem_16_24 | DOI Listing |
JAMA
January 2025
Division of Pediatric Pulmonary Medicine, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, Pennsylvania.
Importance: T helper 2 (T2) cells and T helper 17 (T17) cells are CD4+ T cell subtypes involved in asthma. Characterizing asthma endotypes based on these cell types in diverse groups is important for developing effective therapies for youths with asthma.
Objective: To identify asthma endotypes in school-aged youths aged 6 to 20 years by examining the distribution and characteristics of transcriptomic profiles in nasal epithelium.
JAMA Cardiol
January 2025
National Heart and Lung Institute, Imperial College London, United Kingdom.
Importance: Hypertension underpins significant global morbidity and mortality. Early lifestyle intervention and treatment are effective in reducing adverse outcomes. Artificial intelligence-enhanced electrocardiography (AI-ECG) has been shown to identify a broad spectrum of subclinical disease and may be useful for predicting incident hypertension.
View Article and Find Full Text PDFJ Clin Sleep Med
January 2025
Division of Pulmonary, Critical Care, and Sleep Medicine, UC San Diego, San Diego, CA.
Continuous positive airway pressure (CPAP) is the treatment of choice for obstructive sleep apnea (OSA); however some people have residual respiratory events or require significantly higher CPAP pressure while on therapy. Our objective was to develop predictive models for CPAP outcomes and assess whether the inclusion of physiological traits enhances prediction. We constructed predictive models from baseline information for subsequent residual apnea-hypopnea index (AHI) and optimal CPAP pressure.
View Article and Find Full Text PDFJ Am Coll Cardiol
November 2024
Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA. Electronic address:
Background: Hypertension is common in patients with heart failure with mildly reduced or preserved ejection fraction (HFmrEF/HFpEF), and current guidelines recommend treating systolic blood pressure (SBP) to a target <130 mm Hg. However, data supporting treatment to this target are limited. Additionally, pulse pressure (PP), a marker of aortic stiffness, has been associated with increased risk of cardiovascular events, but its prognostic impact in HFpEF has not been extensively studied.
View Article and Find Full Text PDFTher Adv Respir Dis
January 2025
University of Texas Health San Antonio and the South Texas Veterans Health Care System, San Antonio, TX, USA.
Idiopathic pulmonary fibrosis (IPF) is often regarded as the archetypal progressive fibrosing interstitial lung disease (ILD). The term "progressive pulmonary fibrosis" (PPF) generally describes progressive lung fibrosis in an individual with an ILD other than IPF. Both IPF and PPF are associated with loss of lung function, worsening dyspnea and quality of life, and premature death.
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