AI Article Synopsis

  • Myasthenia gravis (MG) is an autoimmune disorder causing muscle weakness due to disrupted acetylcholine receptors, complicating management during surgeries.
  • A 66-year-old male with severe MG and health complications underwent successful open sigmoid colectomy using epidural anesthesia instead of traditional methods.
  • The case suggests that neuraxial anesthesia could be a safer alternative for high-risk patients during colorectal surgeries, avoiding neuromuscular agents and intubation.

Article Abstract

Myasthenia gravis (MG) is an antibody-mediated disorder that disrupts postsynaptic acetylcholine receptors with consequent fatigable weakness, bulbar symptoms, and respiratory fragility. MG patients can be challenging to manage during open abdominal surgery given the unpredictable efficacy of neuromuscular and reversal agents and the risk of precipitating an MG crisis. Regional neuraxial anesthesia eliminates the need for these agents and endotracheal intubation. Here, we report the case of a 66-year-old male with a history of advanced MG, vasovagal episodes with bradycardia and asystolic arrest, and complicated diverticulitis who underwent an uncomplicated open sigmoid colectomy achieved with epidural anesthesia-analgesia. Neuraxial anesthesia can be considered and further investigated as an effective approach in optimizing high-risk patients undergoing open laparotomy for colorectal surgical care.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11608600PMC
http://dx.doi.org/10.7759/cureus.72842DOI Listing

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