Acquired thrombotic thrombocytopenic purpura (acquired TTP) is a rare clinical syndrome caused by a decreased ADAMST13 activity, leading to systemic microvascular thrombotic events, with high mortality rates when the diagnosis and treatment are delayed. The authors report an acquired TTP in a patient with cerebrovascular disease. The aim is to emphasize the importance of considering atypical acquired TTP clinical presentations in order to optimize diagnostic and treatment approaches, minimize possible sequels, and improve the prognosis.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11608012 | PMC |
http://dx.doi.org/10.7759/cureus.72762 | DOI Listing |
Front Vet Sci
January 2025
Department of Veterinary Medicine and Animal Production, University of Naples, Federico II, Naples, Italy.
Introduction: Ultrasound imaging (US) is the method of choice to assess the canine prostate gland. Whilst recent studies have documented the role of castration in the development of prostatic neoplasia, little is known about parenchymal and perfusion features of the normal and abnormal prostate in neutered dogs. No data are available concerning prostatic changes after the first 90 days following castration.
View Article and Find Full Text PDFJ Immunother Precis Oncol
February 2025
Section of Benign Hematology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Thrombotic thrombocytopenic purpura (TTP) is characterized by thrombotic microangiopathy resulting from decreased activation of the von Willebrand factor-cleaving protease (ADAMTS13). TTP can cause organ damage and is often fatal if the appropriate treatment is not started immediately. Although primary immune TTP is the most common form of TTP, secondary immune etiologies, including complications from immune checkpoint inhibitors (ICIs), have also been reported.
View Article and Find Full Text PDFEur Radiol Exp
December 2024
Department of Neuroradiology, University Medical Center, Johannes Gutenberg-University of Mainz, Mainz, Germany.
Background: Several factors are frequently considered for outcome prediction rin stroke patients. We assessed the value of digital subtraction angiography (DSA)-based brain perfusion measurements after mechanical thrombectomy (MT) for outcome prediction in acute ischaemic stroke.
Methods: From DSA image data (n = 90; 38 females; age 73.
Cureus
October 2024
Internal Medicine, Hospital Central do Funchal, Funchal, PRT.
Acquired thrombotic thrombocytopenic purpura (acquired TTP) is a rare clinical syndrome caused by a decreased ADAMST13 activity, leading to systemic microvascular thrombotic events, with high mortality rates when the diagnosis and treatment are delayed. The authors report an acquired TTP in a patient with cerebrovascular disease. The aim is to emphasize the importance of considering atypical acquired TTP clinical presentations in order to optimize diagnostic and treatment approaches, minimize possible sequels, and improve the prognosis.
View Article and Find Full Text PDFDtsch Med Wochenschr
November 2024
Klinik für Innere Medizin I - Abteilung für Hämatologie und Hämostaseologie, Medizinische Universität Wien, Österreich.
100 years ago Dr. Eli Moschcowitz described the first case of thrombotic thrombocytopenic purpura. For many decades there were no recognized treatment options, and the mortality rate was extremely high.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!