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Preservation of Palatal Mucosa in Rhinomaxillary Mucormycosis Cases. | LitMetric

Preservation of Palatal Mucosa in Rhinomaxillary Mucormycosis Cases.

J Maxillofac Oral Surg

Head of Department of Dentistry, All India Institute of Medical Sciences, Raipur, India.

Published: December 2024

AI Article Synopsis

  • Mucormycosis is a severe, potentially deadly infection that requires quick diagnosis and treatment, often necessitating surgical procedures like maxillectomy for severe cases.
  • The study involved a retroprospective analysis of 32 patients who underwent maxillectomy for rhinomaxillary mucormycosis, focusing on the effectiveness of using palatal mucosa for surgical closure.
  • Results showed that 22 patients had complete flap closure after 3 months and 28 patients had total palatal mucosa uptake at 6 months, highlighting the success of this method in preventing complications.

Article Abstract

Introduction: Mucormycosis is an aggressive, life-threatening infection that requires prompt diagnosis and early treatment. Depending on the severity of the disease, rhinomaxillary mucormycosis (RMM) may necessitate maxillectomy, ranging from partial to total removal. The implementation of primary closure leads to improved functional ability by creating a separation between the oral and nasal cavities, which facilitates oral intake and reduces the duration of nasogastric feeding. This, in turn, enhances the patients' quality of life. The objective of this study was to evaluate the effectiveness of primary closure using palatal mucosa (PM) following maxillectomy in patients with RMM.

Methodology: We conducted a retroprospective study to analyze the outcomes of 32 operated cases of rhinomaxillary mucormycosis (RMM). After maxillectomy, we preserved highly vascular uninfected palatal mucosa to close the maxillary defect. The study spanned 4 months, encompassing 4 months of retrospective data collection and 3 months of prospective data collection.

Results: During the 3rd month follow-up, complete closure and uptake of the flap were observed in 22 patients. At the 6-month follow-up, 28 participants exhibited total uptake of PM, with no oro-antral/nasal communication.

Conclusion: This study concludes that in most circumstances, employing a PM flap to close the defect after maxillectomy and surgical debridement is a successful approach as it reduces the occurrence of oro-antral/oro-nasal communication.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11607237PMC
http://dx.doi.org/10.1007/s12663-024-02129-0DOI Listing

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