This study explores how children experience two different locations at Oslo University Hospital in terms of their architectural design and emotional potential. The first location includes a conventional modern hospital wing, whereas the other is a uniquely designed cabin in natural surroundings outside the hospital building, the Outdoor care retreat. The research is a psychological study of how various locations activate cognitive schemas and lead to elicitation of different emotional responses and modes of behavior for children. Participants included 17 children aged 7 to 16, whereby 11 children had no previous experience with hospitalization for a serious medical condition and 6 children were undergoing treatment or follow-ups related to a medical condition at the time of data collection. The data material consisted of walking interviews accompanied by a semi-structured interview guide. The qualitative material was analyzed by applying reflexive thematic analysis and categorized into themes. Study findings illustrate that children experience the environments differently in terms of physical and emotional restrictions. Overall, the children prefer architectural spaces with direct contact to nature or design that mimics natural environments, in addition to being exciting, friendly, and intimate. In these environments, children feel less restricted, more relaxed and more free to express themselves and a range of emotions. This study proposes that spending time in such environments will increase resilience and hospitalization satisfaction for children admitted to hospitals for longer periods of time. In turn, this could have important implications for practice if included in the design of future health care facilities.
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http://dx.doi.org/10.3233/SHTI240954 | DOI Listing |
Background: An estimated 17% of all couples worldwide are involuntarily childless (infertile). The clinically identifiable causes of infertility can be found in the male or female partner or in both. The molecular pathophysiology of infertility still remains unclear in many cases but is increasingly being revealed by genetic analyses.
View Article and Find Full Text PDFHum Vaccin Immunother
December 2025
Research and Development, Infectious Disease, Moderna, Inc., Cambridge, MA, USA.
Safety, immunogenicity, and effectiveness of an mRNA-1273 50-μg booster were evaluated in adolescents (12-17 years), with and without pre-booster SARS-CoV-2 infection. Participants who had received the 2-dose mRNA-1273 100-µg primary series in the TeenCOVE trial (NCT04649151) were offered the mRNA-1273 50-μg booster. Primary objectives included safety and inference of effectiveness by establishing noninferiority of neutralizing antibody (nAb) responses after the booster compared with the nAb post-primary series of mRNA-1273 among young adults in COVE (NCT04470427).
View Article and Find Full Text PDFJ Speech Lang Hear Res
January 2025
Department of Linguistics and Modern Languages, The Chinese University of Hong Kong, China.
Purpose: This study aims to examine the associations of phonological, lexical, and grammatical skills within and between languages in Mandarin-English bilingual preschoolers.
Method: Sixty-three Singaporean Mandarin-English bilingual children aged 3-5 years were assessed for articulation, receptive vocabulary, and receptive grammar using standardized instruments in English and compatible tools in Mandarin. Regression analyses were performed on each language outcome, with other language variables as predictors, controlling for age, nonverbal working memory, and home language environment.
JAMA Netw Open
January 2025
Department of Surgery, University of Washington, Seattle.
Importance: Timely access to care is a key metric for health care systems and is particularly important in conditions that acutely worsen with delays in care, including surgical emergencies. However, the association between travel time to emergency care and risk for complex presentation is poorly understood.
Objective: To evaluate the impact of travel time on disease complexity at presentation among people with emergency general surgery conditions and to evaluate whether travel time was associated with clinical outcomes and measures of increased health resource utilization.
JAMA Pediatr
January 2025
Department of Pediatrics, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ontario, Canada.
Importance: Detection of congenital cytomegalovirus (cCMV) infection has previously relied on targeted screening programs or clinical recognition; however, these approaches miss most cCMV-infected newborns and fail to identify those infants who are asymptomatic at birth but at risk for late-onset sensorineural hearing loss.
Objective: To determine the feasibility of using routinely collected newborn dried blood spots (DBS) in a population-based cCMV screen to identify infants at risk for hearing loss and describe outcomes of infants screened.
Design, Setting, And Participants: This diagnostic study of a population-based screening program in Ontario, Canada, took place from July 29, 2019, to July 31, 2023.
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