In this issue, Klingbeil and colleagues deploy a paralog co-targeting strategy to reveal microtubule affinity-regulating kinases 2 and 3 as redundant negative regulators of the Hippo pathway and potentially actionable targets in YAP/TAZ-addicted tumors. See related article by Klingbeil et.al., p. 2471.
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http://dx.doi.org/10.1158/2159-8290.CD-24-1349 | DOI Listing |
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