AI Article Synopsis

  • PRRSV is a significant virus affecting the swine industry, and this study is the first to report NADC34-like strains found in Japan.
  • Serum samples from 18 piglets in Okinawa were analyzed, showing all samples matched a specific sublineage, identified as sublineage 1.5 of Lineage 1.
  • Although NADC34-like strains are known to cause severe outbreaks, the farm experienced only a temporary spike in piglet mortality, indicating a need for further research on these strains and the potential for new variants.

Article Abstract

Porcine reproductive and respiratory syndrome virus (PRRSV) is an important pathogen in the swine industry. We report for the first time the detection of NADC34-like PRRSV strains in Japan. Serum samples from 18 piglets in Okinawa Prefecture were analyzed for the open reading frame 5 (ORF5) gene encoding glycoprotein 5, which revealed that all samples belonged to sublineage 1.5 (L1A) of Lineage 1. Phylogenetic analysis, restriction fragment length polymorphism patterns, and glycosylation site characteristics confirmed the presence of NADC34-like strains that caused severe outbreaks in the U.S. and Asia. Despite its known pathogenicity, the farm showed only a transient increase in mortality. These findings highlight the need for further investigation into the pathogenicity of PRRSV strains and their potential for the emergence of new variants in Japan.

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http://dx.doi.org/10.1292/jvms.24-0451DOI Listing

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Article Synopsis
  • PRRSV is a significant virus affecting the swine industry, and this study is the first to report NADC34-like strains found in Japan.
  • Serum samples from 18 piglets in Okinawa were analyzed, showing all samples matched a specific sublineage, identified as sublineage 1.5 of Lineage 1.
  • Although NADC34-like strains are known to cause severe outbreaks, the farm experienced only a temporary spike in piglet mortality, indicating a need for further research on these strains and the potential for new variants.
View Article and Find Full Text PDF

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