Objectives: Sleep is an important determinant of quality of life. Sleep disturbance is concomitant with end-stage knee osteoarthritis for which total knee arthroplasty (TKA) is the most commonly done procedure. However, literature on this topic is lacking in terms of the impact of sleep quality on patient satisfaction after arthroplasty, especially the adverse associations of surgery on sleep quality. Improvement in sleep quality may be a necessary prerequisite for any effective rehabilitation program. In our study we aim to assess the changes in sleep quality after TKA, and how it affects patient satisfaction of TKA and other quality-of-life indicators, postoperatively.
Methods: Over a period of two years, 104 patients undergoing primary total knee arthroplasty were assessed prospectively using the Pittsburgh Sleep Quality Index (PSQI), Knee Society Score (KSS), Oxford Knee Score (OKS); preoperatively and postoperatively at 3 months, 6 months, and 1 year. Obesity and diabetes status were also included in the analyses.
Results: Preoperatively, most patients exhibited poor sleep quality (mean PSQI score 9.23 (Standard deviation (SD) = 3.03), which subsequently improved after surgery. Immediately after surgery, there was an initial worsening in the PSQI scores until 6 weeks (12.58 (SD = 3.59)). However, at 1 year, there was a statistically significant improvement to a mean of 5.69 (SD = 1.91). The mean Visual Analogue Scale (VAS) score showed a statistically significant decrease from 7.26 (SD = 1.90) pre-operatively to 1.80 (SD = 1.37) at 1 year postoperatively (p < 0.001). The mean OKS showed a statistically significant increase from preoperative 18.15 to 33.81 at 1 year and the composite KSS increased from 36.22 preoperative to 87.09 at 1 year (p < 0.001). Improvement in sleep was observed for 61% of non-obese patients while obese patients did not observe any improvement in sleep. Only 8% of diabetics showed improved sleep compared to 55% of non-diabetics.
Conclusions: We observed an overall improvement in sleep quality after total knee arthroplasty. However, there was an initial stage of sleep disturbance immediately postoperatively. Obesity and diabetes may lower the chances of achieving optimal improvements in both functional and sleep outcomes.
Level Of Evidence: Level III.
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http://dx.doi.org/10.1016/j.jisako.2024.100373 | DOI Listing |
Age Ageing
January 2025
Centre for Psychiatry and Mental Health, Wolfson Institute of Population Health, Queen Mary University of London, London, E13 8SP, United Kingdom of Great Britain and Northern Ireland.
Background: Behavioural and psychological symptoms of dementia (BPSD) can complicate acute hospital care, but evidence on BPSD in this setting is heterogeneous.
Objective: To determine the prevalence of BPSD in acute hospitals and explore related risk factors, treatments, and outcomes (PROSPERO: CRD42023406294).
Methods: We conducted a systematic review and meta-analysis by searching Cochrane Library, MEDLINE, and PsycINFO for studies on BPSD prevalence among older people with dementia during their acute hospital admissions (up to 5 March 2024).
Geroscience
January 2025
State Key Laboratory of Brain and Cognitive Sciences, The University of Hong Kong, Hong Kong, Hong Kong.
Aging is associated with disrupted sleep patterns, such as fragmented sleep and reduced efficiency, leading to negative health outcomes. There is evidence of a bidirectional relationship between sleep and gut microbiota, which plays a key role in the gut-brain axis and overall health. However, studies on this relationship in older adults have limited generalizability and show conflicting results, highlighting the need for further research.
View Article and Find Full Text PDFRheumatol Int
January 2025
Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Kocaeli University, Kocaeli, Turkey.
This study aims to investigate the relationship between sleep hygiene and sleep quality in patients with systemic sclerosis (SSc) and to compare the sleep hygiene and sleep quality outcomes across three distinct groups: SSc patients, rheumatoid arthritis (RA) patients, and healthy controls (HC). This study employed an observational, cross-sectional, and parallel group design. SSc-related and RA-related variables, depression and anxiety were assessed.
View Article and Find Full Text PDFChem Biodivers
January 2025
Shanghai General Hospital, department of clinical Pharmacy, 85 Wujin Road, Hongkou District, Shanghai, 200080, Shanghai, CHINA.
Lotus leaves (LL), petals (LP), and seeds (LS) are believed to have properties that can improve sleep. However, their efficacy in improving sleep has not been fully validated. This study aimed to investigate the multitarget mechanisms of extracts from these lotus parts for sleep improvement using chemical analysis, bioactivity assessment, meta-analysis, network pharmacology evaluation, and molecular docking.
View Article and Find Full Text PDFJ Sleep Res
January 2025
Faculty of Psychology and Sports Science, Department of Psychology, Bielefeld University, Bielefeld, Germany.
Pre-sleep worrying is associated with sleep disturbance, which in turn is associated with impaired affective wellbeing. However, studies examining the fine-grained temporal order of these variables are still lacking. In particular, within-person mediation of the association between pre-sleep worrying and the following day's affective wellbeing by subjective and objective indicators of sleep has not been tested yet.
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