Introduction: Norms for mandibular growth are well-established, but they have large variances, and no research has been conducted on how practitioners use them in clinical judgment to guide the treatment of individual patients.
Methods: Co-Pog projections of mandibular growth were combined from the Burlington and Michigan growth studies following statistical adjustments. Cervical measures were also evaluated. Photographs of complete records for 2 males and 2 females aged approximately 12 years with mandibular length matched age and sex norms were presented to 29 practicing orthodontics. Initial treatment plans and changes in treatment, if any, were noted across a projected range in 2-year mandibular growth.
Results: A large variance was noted in the growth norms. Stepwise multiple regression found insignificant improvements in predictions when cervical vertebral maturation scores were added to age and sex. Comparably large variation was also observed across practitioners in their initial treatment plans given common patient information. Moreover, 4 in 10 practitioners would not change their initially proposed treatment, given growth projections varying between 0-7 mm over 2 years. Others were sensitive only to small or large changes or used a range smaller than the variance in the norms. Between a quarter and a third of the variance in changed treatment plans was a function of differences between practitioners, whereas almost none was attributable to expected growth in patients.
Conclusions: This study represents the integration of the established literature with practitioner experience called for in the American Dental Association concept of evidence-based dentistry. It was found that there was substantial variance in both established norms for mandibular growth and the role claimed for precise estimates of growth play in treatment planning. The latter appears to be the larger of the two.
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http://dx.doi.org/10.1016/j.ajodo.2024.10.013 | DOI Listing |
Orthod Fr
January 2025
Nantes Université, Université Angers, CHU Nantes, INSERM, CNRS, CRCI2NA, 44000 Nantes, France
Introduction: The aim of this article is to present the diagnostic and therapeutic approach to unilateral posterior vertical insufficiency.
Material And Methods: The authors describe the management protocol.
Results: Posterior vertical insufficiency (PVI) manifests clinically as obliquity of the maxillo-mandibular occlusal plane and bicommissural line, and deviation of the chin.
Bone Res
January 2025
Université de Paris Cité, Imagine Institute, Laboratory of Molecular and Physiopathological Bases of Osteochondrodysplasia, INSERM UMR 1163, Paris, France.
Gain-of-function mutations in fibroblast growth factor receptor (FGFR) genes lead to chondrodysplasia and craniosynostoses. FGFR signaling has a key role in the formation and repair of the craniofacial skeleton. Here, we analyzed the impact of Fgfr2- and Fgfr3-activating mutations on mandibular bone formation and endochondral bone repair after non-stabilized mandibular fractures in mouse models of Crouzon syndrome (Crz) and hypochondroplasia (Hch).
View Article and Find Full Text PDFAm J Biol Anthropol
January 2025
Department of Medical Anatomical Sciences, College of Osteopathic Medicine of the Pacific-Northwest, Western University of Health Sciences, Lebanon, Oregon, USA.
Objectives: Tooth dimensions typically scale with mandibular and postcranial size in primates, although the exact pattern of scaling varies. This study assesses whether correlations by tissue type, anatomical region, or function (mastication or intrasexual competition) are present and could therefore act as evolutionary constraints on tooth-jaw-body size relationships by estimating genetic and phenotypic correlations between dental, mandibular, and postcranial dimensions in rhesus macaques (Macaca mulatta).
Materials And Methods: The teeth, mandibles, and postcrania of 362 adults from the Cayo Santiago skeletal collection were measured.
J Stomatol Oral Maxillofac Surg
January 2025
Department of Maxillofacial Surgery, Plastic Surgery Hospital and Institute, Chinese Academy of Medical Sciences, Peking Union Medical College. No. 33, Ba-Da-Chu Rd, Shi Jing Shan District, Beijing 100144, PR China. Electronic address:
Objective: This systematic review and meta-analysis aimed to determine the optimal timing for mandibular distraction osteogenesis in children with craniofacial microsomia based on long-term outcomes and relapse rates.
Methods: A comprehensive search of PubMed, Embase, Cochrane Library, and Web of Science was conducted for studies published up to September 2024. Eligible studies included children aged ≤16 years with CFM who underwent MDO, with follow-up duration exceeding one year.
Narra J
December 2024
Department of Animal Production and Technology, Faculty of Animal Science, Institut Pertanian Bogor, Bogor, Indonesia.
Previous studies of IIA-1A5 have shown its potential as a probiotic in modulating gut microbiota and providing health benefits; however, its effects during pregnancy remain underexplored. The aim of this study was to assess the safety of fermented milk enriched with IIA-IA5 in pregnant mice. An experimental study was conducted at Universitas Andalas, Padang, Indonesia.
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